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Generic Name: Oxycodone Extended-release Capsules

Brand Name: Xtampza ER

Xtampza ER Drug and Medication User Reviews

xtampza requires 4500 calories of food to fully activate and does not really activate at all as far as I could tell. I went into withdrawals on it.


Hi fortunately this medication doesn’t work and on top of that, who could really afford to take it. I promise you it doesn’t work. If it does work then the pain is in your head and not your body.


I've tried other opioids but this medication xtampza er was the worst. No relief at all. It takes around 3 to 4 hours to kick in but only last about 4 but it states to take every 12. This medicine should've been tried on someone who really lives in chronic pain like most of us that are commenting on this site. I have been living in chronic pain since 2014 this pain is NO JOKE!!! You're lucky yo even get 3 or 4 hours of sleep a night. Then you have to deal with the pain during the day. You don't have the pleasure to enjoy life. I hope by some miracle someone will create a wonder drug that really can help with this unbearable pain I live in..no quality of life


Have to take at least 144mg on a full stomach to get a few hours relief. It takes 3-4 hours to kick in and only lasts about 4 hours once it does.


After a couple injuries I’ve developed Spondylolisthesis (2.5)as well as spinal canal narrowing and disc failure. I started on tramadol a few years ago and as my condition worsened I take 40-60mg of oxycodone per day. As my conditions worsen and my tolerance increased the doctor put me on fentanyl parches but I hated the way they made me feel. He changed to this medicine and it does nothing for my pain. I get a weird feeling when taking it like I’ve had too much caffeine. I feel like this medicine was developed after the Purdue debacle and wasn’t properly tested before hitting market. Just reading the reviews here and seeing how little this helps proves it’s not effective. Doctors are running scared of prescribing pain medication which has had the effect of denying real chronic pain patients of a necessary dosage. Whatever the answer is it’s not this stuff. I’ve since turned to the dark net, which at my age is ridiculous, to properly medicate so my quality of life is manageable.


I have Ehlers danlos syndrome type 3. I switched from interthecal pump to 18 mg every 12 hours of this . I also have malabsorption. I am warning anyone with malabsorption DONT try this. I am in severe withdrawal now because it just can't be absorbed into my body. ??


After 3 years of this med at night I received no pain relief at night from it. I live where there is only one pain management doctor in fifty miles. I am between a rock and a hard place. My doctor does not seem to care about treating any other pain than my original problem. OxyContin keeps my pain relief during the day if I sit and do not stand for more than a few minutes at a time. I am housebound but my doctor doesn’t seem to care.


I have been a pain patient for nearly 20 years due to Ehlers-Danlos syndrome. Previously, my pain was managed with a combination of extended-release morphine and hydrocodone. My new doctor wanted me to try other long-acting medications because they didn't like the side effects of morphine. I felt the same way, so I was fine with this and went into it with a good attitude. Their first choice was Xtampza, and my experience has completely shattered my confidence in my doctor and this process. My medication was switched from generic MS Contin 15mg twice a day to Xtampza 13.5mg twice a day, which is an increase. This is the worst medication I have ever tried, and I'm including medications that landed me in the ER. I am firmly convinced that this medication was manufactured to scare people away from opioids. A few reviewers used the word "torture" - this is accurate. From the very first day, I had diarrhea, chills, and hot flashes. My digestive system felt like it was writhing the entire time on this medication - literally like I was crawling with worms. I had pain in parts of my body where I never had pain before, or where pain had been well-managed previously. I stopped dreaming completely and developed terrifying intrusive thoughts, as well as extreme mood swings (either toe-tappingly happy or sobbing). This medication would either hit too hard or not work at all. I tried taking it with a fatty meal and I think I must've overdone it because two hours later I was frighteningly high, and later in total withdrawal for the last six hours of my dose time. Being in withdrawal made me crave taking more medication early, which I did not do. You cannot eat the wrong thing at the wrong time with this stuff or you will be shaking in bed, wondering if you should break out the Narcan (I left the Narcan on my bedside table and told my family to check on me). I tried both taking the capsule whole and sprinkling it on food (the same food every time) and every 12 hours was a totally different experience: some were fine and others were torture. After about three days of sprinkling the capsule contents onto food, I developed a prickly itch in my throat and rectum, as well as feelings of impending doom. It was at this point that I called my doctor, who emergently switched me to enough hydrocodone to cover me until my next appointment. I tried so hard to make this stuff work, but then came to the conclusion that your medication should work for you and not the other way around! At no time did I feel safe taking this medication, and it has left me terrified to try anything else and suspicious of my doctor's motivations for switching my medication.


This product has a difficult wax based coating that can only be dissolved by certain foods, period. Try your own or take a look at my suggestion. Finally, it works for almost 10 hours if you are lucky but you should get 8 hours without issue, with relief starting at about 75 minutes and good relief around 2 hours. Two soft boiled eggs, or one but the yolk is what will dissolve the coating. Adding a small breakfast link sausage will help. And when you take it, sprinkle it in 1-2 tablespoons of virgin olive oil. This actually will help some people with their cholesterol but see nutrionist reviews on unsaturated fats and benefits of virgin olive oil. It's ridiculous patients have to suggest to their doctors, even experts, how to take this because the manufacturer won't and isn't going to put this in the patient information section. If you don't take lipid soluble foods, it simply won't work (applesauce makes zero sense). And, eat fifteen minutes before taking the medication and always wash down with 4-8 ounces of water.


It works for over night although I find ER pain Med was worse because I would sleep through the whole night and not use the restroom and wake up in worse pain due to a bladder disease and it making me tired and not wake up to pee. Tell your doctor even if it works a little. They will find something better, if you have a good one. They don’t want you in pain and miserable. I spoke up and even wrote a pain log of how it affected me all day for a few days. Iv tried many and I was hoping this would be it but unfortunately it wasn’t. I also didn’t know about eating with it to make it work better. It made me feel antsy but sleepy at the same time. I’m sorry to everyone struggling with chronic pain like myself. I know it’s horrible but don’t give up speak up and tell the truth.


Coordinating with meals difficult. Long uptake time. Narrow analgesic window. 12 hour duration is false, even with strick meals compliance.


Doesn't work. What a nightmare. Torture.


I have been a chronic pain patient for over 20 years. I had been on OxyContin ER 40mg twice a day. I was given Oxycodone for breakthrough pain. I was now switched to Xtampza ER 36mg which is supposed to be equal to the Oxy 40s. It’s a joke. They don’t really tell you how much HFHC food you need. I have found that sprinkling it on food is somewhat better. I usually have a cup of pudding and sprinkle it on that. But one takes forever to kick in and I don’t feel any relief. I realize I’ve grown quite tolerant to this. I’m only allowed 3 Oxycodone per day for breakthrough pain. Most times I need to take those three at once to get any relief. I tried doubling up on the Xtampza ER but still nothing. The pain I encounter in my legs and back is excruciating. I’m waiting to get a new MRI but in the mean time the doctors don’t want to increase the dosage. It’s been hell living with this pain. I’m lucky if I can sleep two hours straight per night. I just don’t know what else to do. I’ve been on Gabapentin and that did nothing for me. I’m also HIV+ so that adds to my discomfort. I feel like the CDC wants to just watch us all die from this pain. There must be something we can do to get the CDC to understand what we are going through.


It puts my stomach in knots 24 hours around the clock even when I eat with food which you're supposed to, it doesn't last 12 hours it lasts eight hours so you go through withdraws if you don't have breakthrough medicine


I like xtampza because it lasts all day. I was reading some reviews and while it's true it takes awhile to kick in most people don't know that you have to eat something with it to get the full effect. Most pain meds work without food but Xtampza you HAVE to eat for it to work properly. Doctors should let their patients know this when they prescribe it.


Very minimal pain relief. I feel that Xtampza brought on more pain, and I began to have pain in places where there was no pain previously, to wit, my right hip.


My only issue is how long it can take for the meds to work. Usually takes about 2 to 3 hours to kick in. Everyone's body is different but I have been experiencing abdominal pain for over a year that I was taking 30mg of morphine 3 times a day for. Now I take 1 of these pills 2 times a day. The pain relief is a lot better


My xtampza has not worked for me. I started at 7mg now on 13 mg. Still so much pain! I’m afraid to complain because I don’t want the little I DO have taken away because I need all the help I can get even if it only takes a fraction my pain away. I just don’t understand why it isn’t working.


I used OxyContin for 22 years. Due to a multitude of problems (4 spinal surgeries, including 3 fusions; remaining ruptured disks; osteoarthritis, to name a few), I had found Oxy to be the ONLY medication that helped with the pain. I had tried Fentanyl (made me want to rip my skin off) and even drip morphine, which did nothing to abate my pain. I agree that the purported 12 hour life of Oxy did not work for me, so I took the medication (80 mg) 3 times daily at 8 hour intervals. In December of last year, my insurance company told me that Oxy would NO longer be covered as of January 1st. If I wanted to use it, my cost would be $3,000/MONTH. Accordingly, my doctor switched me to XtampzaER, the purported non-addictive Oxy. My experience has been that XtampzaER has done little to abate my pain. I thank God for Gabapentin, which I am also taking for ‘chronic and acute neuropathy’ resulting from nerve damage in one leg. Were it NOT for Gabapentin, I would be unable to get out of bed. The greatest area of efficacy for XtampzaER is in constipation - literally a Pain in My Ass! Am working with a nationally-known pain doctor at a major US teaching hospital who has NEVER prescribed this medicine. Am know hoping to wean off this and try almost anything else as this stuff is overpriced junk!


Takes forever to kick in and then barely helps for 3-4 hours. Many side effects. Would not recommend for anyone if you have better plan. I was forced onto this non-“miracle” drug. Run don’t walk away.