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Generic Name: Saxagliptin and Metformin HCl Extended-Release

Brand Name: Kombiglyze XR

Kombiglyze XR Drug and Medication User Reviews

I am 50 ,from last 04 year i am taking this medicine,i saw my sexual life is in downside,but sugar level always control.


Switched from metformin and glipizide to Kombiglyze. My A1C dropped significantly and my blood sugar level was more consistent. I didn't have the hypoglycemic episodes like with glipizide.


I use Kombiglyze as a supplement to injected insulin. A1c improved marginally over Metformin as a supplement to insulin. Will reassess Kombiglize vs Metformin due to cost - tier 4 vs Tier 1 for this newly retired. No,side effects. Would continue were cost not an issue.


I have been on this for a bout a month and have had constipation, diarrhea, and headaches, etc. It works but I'm really worried about the whole pancreas side effects I read about.


Don't ever take this drug it will cause much damage to your heart and brain. I was on this family of drugs for almost four years could not sleep almost lost my job memory loss, muscle pain, using the bathroom all the time. Now off because of much anxiety, sick to my stomach.


Like all medications, this one also has its affects but luckily I did great on this one. My AC1 went down within 3 months and it was easy on my stomach.


I had some stomach issues at 1st but after about a month they stopped. My A1C was 10.5 and after about 4 months of taking Kombiglyze it was 7. I don't diet and exercise :(.


I have been taking this drug for about 3 months, and the effects have been instant. I don't have any side effects. My blood glucose dropped from over 400 to a constant 80 to 100 through out the day. I take the 2.5/1000 pill once a day. I was taking insulin multiple times daily but since starting the kombiglyze I no longer require the insulin shots. I pay the $10 monthly with great satisfaction.


not to happy with it been very sick because of it but will keep taking for another week to see if my body will adjust to it


I was on this drug for 4 months and it until I found out my niece, who was on it for a little less than 2 years, developed pancreatic cancer in her early 40s with no family history of any cancer. I then came across a New York Times article (Google: Dr. Peter C. Butler New York Times) where they discussed many studies and warnings about this class of drugs and pancreatitis and pancreatic cancer. I have since stopped taking this and working on diet, exercise and going back to humalog/humilin to get my sugars in check. Please research this drug fully before continuing or starting it!


This medication has worked great for me. I've lost 50 pounds with a combination of exercise, proper nutrition and this medication. I am very happy with the results.


47 Male Glucophage did not lower my blood sugar enough so the DR. put me on this. Does :5/1000 If you get headaches it is because your not drinking enough water. Stomach issues will last about 3 weeks and again water or Powerade zero helped alot. Be sure to take with food, as the effect is much more noticable. When I took this with anything that had aspertame in it (coke zero) I got bad gas pains. I do not get those pains with Splenda.


Just started. It is expensive. One review mentions a card used to register with the Manufacturer. It reduced her cost to $10 a month. I would like to know more about this.


I've only been on it for 3 days. However, I've had lower stomach pain, persistent pain in my left shoulder, and body aches so far. How long do I continue to see if they subside? BG numbers haven't dropped much yet.


im having serious leg cramps in my lower right leg only. Not sure if its from the medicine but am going to check with my doctor


I Take 1 metformin pill along with 1 Kombiglyze in the am and then 1 metformin in the evening..No side effects and my surgars have improved noticeably...