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Generic Name: Ludiomil (maprotiline)

Ludiomil Reviews

For Panic Disorder "I have been on maprotiline for over 20 years to treat my panic disorder. It was the only medication that worked and I tried just about all of them (tricyclic antidepressants, MAO inhibitors, Prozac, Wellbutrin). Hands down, this medication had the least side effects and the best coverage. I have been living a full life, panic free."


For Depression "I had been on Ludiomil for over 30 years, and they discontinued it. I went on the generic maprotiline, and now they're going to stop it too. I'm beside myself. I have about another month, and I will be out. This medicine saved my life. I can't believe they could just stop making it for those of us on it. They say it is not addictive, but let me tell you I have tried several times to get off of it, and I get all the same symptoms I had over 30 years ago on top of the withdrawal symptoms I'm going to get. Life is about to go bad again. The doctor and I talked, he says he won't mix maprotiline with any other medicine, and I'll have to be off it for 2 weeks before starting another medicine. This will put me into a severe depression. Nothing else works."


For Depression "I tried Ludiomil over thirty years ago when I was severely depressed. Of all the different antidepressants that had been prescribed for me (amitriptyline, doxepin nortriptyline, desipramine, trazadone, etc.) Ludiomil was definitely the most effective of the ones I tried. Unfortunately, it like Remeron (which I tried years later) raised my liver enzymes and I was told by my physician (I was seeing a psychiatrist at the time) to discontinue using it. But I was lucky: just before I was scheduled to undergo electro-shock therapy to cure my intractable depression, I learned that I was allergic to the milk protein and after removing it from my diet I never again had the deep melancholy I had experienced before."


For Major Depressive Disorder "I was pleased with the results of this medication. Eventually i was able to discontinue taking this medicine after 8 months."

More about Ludiomil (maprotiline)

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  • During pregnancy
  • Drug class: tetracyclic antidepressants
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Patient resources

  • Ludiomil advanced reading

Professional resources

  • Ludiomil prescribing information

Related treatment guides

  • Major Depressive Disorder
  • Depression