Generic Name: Mekinist (trametinib)
Mekinist Reviews
For Melanoma, Metastatic "Have been on Mekinist and Dabrafenib for 2 weeks only. So far melanomas have reduced in size. Blood test results were good. Hoping it continues but I must stress it is only early days for me. Two combined drugs are working as they should. Some nausea, aching and itchiness. But taking antihistamines. Melanomas are in spine so pain expected."
For Melanoma, Metastatic "Stage 3 metastatic melanoma, tried Keytruda, did not work, tried Zelboraf and Cotellic, made me sick, sick, changed doctor. I am on Tafinlar and Mekinist for 7 months now. No cancer recurrence. Mild side effects include moderate dizziness, intermittent diarrhea, weight loss, intermittent nausea. Muscle fatigue and soreness. Occasional headache. No fevers. All tolerable! Clean scans!!! Most importantly, Taf 2 tablets 2 times a day, Mek 3 tablets 1 time a day. The biggest challenge is taking them on an empty stomach. I am also a type 2 diabetic. My sugars have risen quite a bit and I have had to double my metformin. That's not fun."
"side effects for me included extreme dry skin, itchy and peeling on feet, pustule’s on face and arms. Was on drug for 8 days had severe reaction. Taken off for 8 days put on prednisone to reduce side effects. Now back on pill much lower dose One tablet every other day. I have no idea if this drug will work on the tumors - I am taking Mekinist for ovarian cancer. This drug has serious side effects. I’m not sure my body will tolerate it."
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