Generic Name: Nurtec ODT for Migraine (rimegepant)
Nurtec ODT for Migraine Reviews
"Within 20 minutes of taking Nurtec ODT, I had the nausea, which I had read about. I took some Zofran, but it didn’t even touch it. Then I had diarrhea and horrible stomach pain, as well as really intense reflux. It felt like I was swallowing fire, 17 hours and counting now. The worst part of this is my migraine isn’t even all the way gone! It is definitely diminished but not gone. I have never written a review on here, but this has been such an awful reaction I knew I had to. I will never take this again. Everyone is different, but for me, this has been a really terrible experience."
"Took my first Nurtec dose on day 4 of a stubborn migraine/cluster (I've gotten conflicting diagnoses) plus neck pain. All pain was gone in less than an hour; no side effects. Sadly, almost 24 hours later, the pain is coming back. That's not a shock, since Nurtec isn't expected to prevent these headaches. My first impression is that Nurtec is faster than triptans but maybe not ideal if you get clusters. Unlike the triptans you can't take another one less than 24 hours later. If pain returns sooner than 24 hours later then maybe stick with triptans. (I'm also taking Aimovig 140 so I shouldn't be getting any of these dagnabbed headaches at all.) And I agree that the packaging is insanely wasteful and also rather difficult. When I'm in that much pain it's hard for me to jump through a lot of hoops."
"I’ve had migraines for 15 years now. I get terrible menstrual migraines and occasional migraines from weather and stress. My migraines begin at the base of my skull and then the sharp pain wraps around to my eyes and forehead as the migraine progresses. Minimum of 4 per month. Nurtec is the only thing that has ever worked, it feels like a miracle. It takes about an hour to work. About 50% of the time, I have a lingering mild headache. I will then take 2 ibuprofens and become headache-free. I have noticed increased bowel movements sometimes, but no nausea. I feel Nurtec has changed my life! I am starting to take it preventatively every other day this month instead of just when a migraine begins."
"Warning - Nurtec contains sucralose, a sugar substitute that can trigger migraines. I saw this after I tried it. The medication did nothing for me, no side effects other than a continued migraine made worse by sucralose."
"I have had migraines for 30 years and hemiplegic migraines for about 10 years. I've taken just about all migraine prevention meds and usually use Imitrex injection to get rid of migraines, but because I recently started having breathing and heart racing with Imitrex, I tried Nurtec again. First, second, third time intense nausea and vomiting. Now 4th time, migraine pain spread to both eyes and is getting worse. I've been on Aimovig, Emgality, and now Ajovy with no results. Botox caused migrainous syndrome, and I ended up with a paralyzed neck. I am sadly disappointed in all CGRP meds, including Ubrelvy."
"This is the 1st negative review of a medicine. For me, this Nurtec ODT medicine never touched my migraine. Actually, my lips and tongue felt as if they had been sprinkled with cayenne pepper, but never swelled. Then, the metallic taste came on. Everything I tried to eat tasted horrible. After that, the stomach cramps and pooping began. Beware of this medicine. Maybe it will work for you, but I had a bad experience and will not use again."
"This is the only drug that's actually worked for my chronic migraines. I also use neurobotox as a preventative, but it hasn't been preventing much lately. I get occipital migraines that last 3 days constantly. They come with nausea and hypersensitivity to light and computer screens, which is debilitating since I work in an office setting. I started Nurtec in February and it's saving my life right now. One pill lasts 2 days, and it destroys the migraine and the nausea. It always takes 40-45 minutes to kick in. My migraines tend to come on in the night, so as soon as I wake up with one, I take a Nurtec and wake feeling better. These are keeping me functional since my migraines have been so much worse this year."
"I had a bad experience with Nurtec. After one dose, Nurtec caused severe nausea which started about 15 minutes after the pill dissolved. The nausea was the worst I have ever experienced, and it lasted for about 18 hours. The nausea was so severe that I was unable to function for the entire time. The nausea led to vomiting, which lasted 2 hours, but it didn't relieve the nausea. Zofran also did not relieve the nausea, and then my doctor called in Reglan, which seemed to help. Nausea is a known side effect of Nurtec, but I certainly do not think anyone would expect this kind of toxic reaction. Be careful with this medication."
"I have taken around ten Nurtec tablets now over the course of two months. Each time I take it in the early stages of a migraine. It takes about an hour to be effective enough that I can tell I still have a migraine slightly, but there isn't pain. I haven't noticed any side effects, which is pretty strange for me. I have tried so many medications for my migraines, and I always have strong negative reactions to the drugs. I am very pleased to have found something helpful!"
"My doctor gave me samples of Nurtec ODT to try for my next migraine. On Sunday (May 9, 2021), I woke with a migraine and tried one. The taste was pleasant, like soft peppermint. Unfortunately, the medication did not help at all. My headache persisted at a milder degree but was still a migraine. It did make me VERY sleepy and inebriated—slurred words, goofy comments, etc. After 4.5 hours with no relief, I called my pharmacist to see if there were any interactions with taking my old medication to knock the migraine out. He said it was okay since they are completely different classifications of medicine. My old meds knocked the migraine out within 1.5 hours. The grogginess and inebriation stayed with me for 36+ hours! It wasn't my old medication because it doesn't do that. Nurtec ODT did not work for me. I give it a 1 out of 10 because it tasted nice."
"This medication does help my migraine headaches I get. It will help them for a few hours. However, this medication gives me the worst abdominal pain ever. It’s a very sharp stabbing pain that only occurs when I take it. It also makes me very tired."
"I called to get the prescription on day one of a migraine, so by the time I got to take it, it was morning of day two. It says to take it at the onset, so I was uncertain of the effectiveness of taking it mid-fully established migraine. I was pleased to have the headache gone quickly with no side effects (I was tired and took a nap, but that might just have been 'Saturday Syndrome'). It's Sunday now, my weather trigger is still present, but I'm feeling pretty good - perhaps a little stiff at the base of my skull, but nothing I can't easily ignore. Happy with the medication. Thrilled with the $0 copay offer. Very concerned about being able to afford once that offer expires."
"My neurologist gave me this to try as an abortive medication along with one other to compare. The other was Ubrelvy. So I took this one when I had a migraine, and I noticed immediately it made my stomach queasy. It didn't last, so that was good, but I was dizzy. I had a slight case of vertigo. When I went to lay down, I started kind of spinning. I was trying to wait it out and fall asleep, but I just felt weird. But my head did start to feel better. But now I am in a haze and don't think I can go to work or do anything around the house. I just feel like I have the flu. I don't like this feeling. I think I preferred the other medication because I didn't experience these side effects."
"I was very hopeful Nurtec ODT would be an effective addition to the Botox for treatments I already receive. As I have been a migraine sufferer since childhood and have had minimal relief. Unfortunately, I experienced more side effects than what are listed. One hour after taking it, I developed slight nausea with significant reflux. I was delayed, light-headed, under the influence, and could hear/feel my heartbeat loudly. I took it during my workday and had to get a ride home since I did not feel clear enough to drive myself. My headache remained and I felt so “stoned” that I went to bed at 8 PM and slept solid until 4 AM. I awoke still with a headache, but no longer stoned. I spoke with my neurologist and explained my experience. He has advised me to discontinue use. I feel they should include a warning not to “drive or operate heavy machinery until you know how it affects you.”"
"First of all, I tried it once and NEVER again. I am allergic to peppermint, and nobody told me it was peppermint flavored. This causes automatic vomiting and nausea! I ate some Jell-O just to try to keep it down. It did not work, made me severely dizzy and nauseated, woozy, and I really thought I was going to just faint. It was horrible. NEVER again."
"I was prescribed Nurtec in 2020. I was skeptical at first but decided to try it. My migraine was really bad, and I had a difficult time opening the packaging, especially being in that much pain. My migraine went away quickly, and I started to feel better. When my migraines quickly came on, I would take one. I am now on my third pack of 8 pills. Now when I take one, my stomach hurts really bad, almost like ulcer pain. I know it is the pill because as soon as I take it, within an hour, I now get a gnawing sensation in my stomach. It lasts all day long and even into the next day. Prilosec will calm it down. Now that I am now getting pains in my stomach, I am now getting diarrhea from Nurtec. I usually never have diarrhea. Now I am starting to question if this medication is safe for my stomach and what it is doing to the lining of my stomach. I will only take this medication now if the migraine won’t subside in a day or two."
"This works great for me! I am unable to tolerate triptans and Topamax, so they did not work for me. Aimovig injections helped, but after a year, I started getting more migraines again. So then I tried Nurtec, and it helps stop my migraines. In the past, my migraines would last 2-3 days, but with this new medication, they are gone the same day!"
"Nurtec ODT medicine gave me a worse headache by 100x than what I had already. It made things far worse and amplified my problem to the 15th power. Stay away from this medicine unless you want problems! ZERO STARS."
"I have used this 3 times. The first two times it worked really well for menstrual-related headaches. No rebound, no side effects. The third time, I got dehydrated and it turned into a migraine. I think I took it too late because I thought rehydrating would make the headache go away. It worked, but took much longer. It took the edge off after 30 minutes, but the headache did not go away completely for about 6 hours. I am using samples given by my doctor. The packaging is really ridiculous. Way over the top and too much waste and frustration trying to get to 2 little pills. Please be more eco-conscious. You should be ashamed of this."
"This medication was terrible. I am on Aimovig and still have to take triptans, so was hoping Nurtec could replace the triptans. It made the migraine worse, and I was increasingly drugged up and with more pain. Really disappointed it had such a horrific effect. I hope someday they come up with something better than triptans."
"Wondering why on earth a company would make a migraine medication with such a common trigger in it-artificial sweetener? I had high hopes for this medication because it acts on CGRP, but it didn’t help my migraine because it has artificial sweetener and flavor in the melt."
"I had taken Nurtec several times over 5 months as needed to abort attacks. It did help but the attacks just came back. At first I didn't have many side effects, but over time I seemed to have more side effects each time I took it. I started to have terrible heartburn and bad stomach pains and my gut just felt horrible in general after taking only 1/2 pill. I also had severe tiredness, dyspnea, and I seriously would get a cold after each time taking it. Then recently I had a really stubborn migraine and took a few doses throughout the week trying to end the attack and suddenly it made my migraine MUCH worse and I had trouble breathing. I also developed SEVERE panic attacks and psychosis!..then I ended up in the ER with a hypertensive crisis. My BP was out of control and not going down (165/115). Got treatment for that but it took weeks to feel completely normal again. This was among the most terrifying experiences of my life. Use with caution! (I'm an otherwise healthy 33 yr old man)"
"Nurtec is not working for me. But not much else is either. I have also tried Ubrevely, and I just started with Emgality injection. Only twice so far. No help yet. I have had these headaches every day lately, well for the last several months. I do have an MRI scheduled to make sure it's not something else. Nurtec worked for me twice in 3 months."
"Every time I took Nurtec, the strong mint taste made me nauseated. It took 4-6 hours to work and made me feel super sleepy. My migraines treated with Nurtec frequently came back later that day, and I had to wait 24 hours after the first dose to take another. My neurologist switched me to 100 mg Ubrelvy, and I find it works much better and faster."
"Took it twice and it does work. Takes about 2 hours for full effect. Doesn't completely eliminate the migraine. I can feel it trying to creep back up at times. Doesn't work up to full 48 hours as commercial says but it doesn't make me tired and feeling drugged so I can take it and carry on with my day. I haven't noticed any side effects at all which is a first for a migraine medication. Having said that I'm not entirely comfortable taking this drug as it's very new and it just seems too good to be true that there are no side effects."
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