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Generic Name: Solu-Medrol (methylprednisolone)

Solu-Medrol Reviews

For Inflammatory Conditions "I was diagnosed with acute laryngopharyngitis which inflamed my throat, tonsils, and mouth. My body didn't react to amoxicillin, so I spent a whole weekend in severe pain. Went to my doctor's office at 10 am on Monday, was hospitalized by 1 pm, received Solu-Medrol by 2 pm, and was pain-free by 7 pm. Over the course of three days, I was very moody, experienced stomach and chest pain, constipation, and couldn't sleep, but once discharged after 3 days of treatment, I was back to my old self within 48 hours. The side effects are bad, but the effects are heaven-sent for pain and inflammation. I have heard the same about Multiple Sclerosis and gout sufferers. God bless you all!"


For Inflammatory Conditions "I have severe COPD that was exacerbated by bronchiolitis, which landed me in the hospital. It has really helped reduce the inflammation in my lungs, and I can finally breathe again. I am on a pretty high IV dose, but they are treating me well. It certainly has side effects. My gut is all pooched out, and I gained seven pounds in a week. Major bloat going on. Heartburn, too. It makes me a little hyper, and my skin is sensitive. I have a back/shoulder ache, but that could be the hospital bed. I hope the side effects go away when I am off of it, but at least I can breathe again."


"I have multiple sclerosis and take Solu-Medrol through an intravenous infusion. I have taken it three times, and it seems to get rid of the symptoms, I get through my MS attacks very quickly. Sometimes it works right away (within hours), sometimes it takes the full 5-day treatment. Even if you do not immediately feel like the symptoms are getting better, it doesn't mean that the Solu-Medrol isn't working. It is, in fact, stopping the attack of the brain. The only thing that I do not like is the metallic taste you get in your mouth. Also, there is a really odd urine smell that comes out through your pores. My blood sugar levels go up when on Solu-Medrol, but the body usually corrects this."


For Gout, Acute "Sometimes takes several hours to work after being administered, but usually relief is dramatic. Best medication I have had to relieve the pain and swelling after an acute attack of gout without having a cortisone injection in the joint. The injection in the joint is very painful but works quicker, but IV treatment is the best route."


For Multiple Sclerosis "A very effective drug for stopping MS relapses. I have had about 7 courses of treatment (over approximately 20 years) consisting of infusion of 1 gram per day of solumedrol for 3 consecutive days. Pretty brutal side effects: immediate metallic taste in mouth after commencing infusion; persistent agitation or feeling wired; difficulty sleeping; spikes blood sugar. All side effects disappear shortly after conclusion of infusion therapy."


For Inflammatory Conditions "I have had to be on this medicine 2 to Three times a year for the last three years. I wish I was able to give it to myself instead of being admitted everytime. Not sure if insurance covers it but it would be worth looking into."


For Asthma, acute "Helped tremendously. Was given as daily injection (by IV) before bedtime during treatment of severe episode shortness-of-breath requiring hospitalization. Reduced need for daily inhalators and restored breathing capacity. Has been two weeks since last dose without any "COPD-Flare" episodes. More effective than Predinisone (pill) for long-term control of condition."


For Immunosuppression "I have had repeated Solu-medrol success use for Systemic lupus erythematosus (SLE). If given enough the first time, it doesn't need to be repeated and I can have had remissions lasting for 18 months to over 2 years living a normal, productive life. The drug is not used enough for this disease unless SLE is life threatening. This drug should be used more to prevent life threatening SLE issues."


For Asthma "My asthma attack and fever of 102.6 started suddenly 1/18/2010. I went to my pulmonary doctor 1/19. I received a Solu-Medrol dosepak. The first days dose is the heaviest. I took it as directed. I had taken 2 doses on the second day when I developed severe chest pains. I returned to my doctor and was admitted to hospital for cardiac work-up. Within 24 hours of tests, I was discharged. I never had any more chest pain after stopping medicine. I must have developed a sensitivity last May when I had pneumonia for 16 days in hospital. My body is very sensitive to medicines. I liked Solu-Medrol. Maybe I have to take it with Benadryl. I don't know until I speak with my doctor on my return visit."


For Inflammatory Conditions "I was rx'd Solu-Medrol for MS numerous times, worked great every time until they gave me straight saline solution because steroids worked too well and were cheap, and they needed to test the new untested and extremely expensive DMDs {disease modifying drugs} for MS on me because I have the chronic type, but they are all designed to limit relapses, and they claimed they needed to see if it slowed progression. And since my first neurologist refused to prescribe it for me anymore, no neurologist will even consider it. Every time it was administered I felt like Popeye after he ate a can of spinach, and I would get the typical side effects; acne, water retention, endless appetite, etc. After all the DMDs started hitting the market, suddenly the Solu-Medrol had absolutely no affect whatsoever. It felt as effective as pure water, with all of the side effects of pure water."


For Asthma, acute "Miracle for acute asthma attack"


For Inflammatory Conditions "Given 1 gm/day x3 days intravenously for MS flare. Symptoms relieved quickly. 3 hrs sleep per 24 hr period, strange metallic taste. All with it though."


For Asthma, acute "This medicine helped my asthmatic flare up and breathing. The site where injection was done was painful. The results of this medicine was a blessing of relief!"


For Asthma "Great working medication."


For Allergic Rhinitis "Used it for a rash (allergies). Having pretty bad join/muscle aches. Hope it passes soon."

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Patient resources

  • Solu-MEDROL injection drug information
  • SoluMEDROL (Advanced Reading)
  • Solu-Medrol

Other brands

Medrol, Medrol Dosepak, Depo-Medrol, MethylPREDNISolone Dose Pack, ... +2 more

Professional resources

  • Solu-Medrol prescribing information
  • Methylprednisolone (AHFS Monograph)

Other brands

Medrol, Depo-Medrol

Related treatment guides

  • Asthma
  • Asthma, Maintenance
  • Allergic Rhinitis
  • Allergies