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Generic Name: Vyzulta (latanoprostene-bunod-ophthalmic)

Vyzulta Reviews

For Glaucoma/Intraocular Hypertension "I was having migraine headaches and vision problems. My doctor sent me to an ophthalmologist who ran tests and discovered my eye pressure to be high 23 & 26. Because glaucoma runs in my family and seems to be hereditary, (and to prevent damage to the ocular nerve and blindness), the doctor prescribed Vyzulta. After one week, the eye pressure decreased to 13 & 15. So now I take one dose (one drop), in each eye every night. After 1/2 hour of the dose, I take Systane for dry eyes. Now my vision is also better! (Side effects: redness, sore, itchy, burning sensation of eyes.)"


For Glaucoma/Intraocular Hypertension "Used Vyzulta for about a month and a half. Pressure went from L25 R22 down to L19 and R18. Only issue I had was a slight stinging when I put the drops in but that disappears after about 5-10 seconds. No eyelash extra growth or dark circles at this time. This didn't dry my eyes like Lumigan. If it didn't sting I would have given a 10."


For Glaucoma, Open Angle "I am using Vyzulta in combination with Cosopt PF. I have been on Cosopt PF 2/day for over a year but needed a second medication. I have tried several. So far with Vyzulta at night my eye pressures have been 11/12 and my eyes feel calmer and look better. I hope this combination will be effective for long term."


For Glaucoma/Intraocular Hypertension "VYZULTA is my 6th drop. Pressure was in low 30’s. Haven’t gotten it checked yet. In my 2nd week with zero side effects. All other drops wreaked havoc on my eyes and on one I nearly passed out from."


For Glaucoma, Open Angle "I've used Vyzulta for about 6 months. It was prescribed to lower my IOP from 18/16 to the lower teens. It has not been effective for me. The lowest I've gone is 16/14, but due to OCT scan showing changes doc wants it down to lower teens 12/13, etc). I am also taking Timolol in the daytime with it."


For Glaucoma, Open Angle "Used Vyzulta for 14 months and suddenly became allergic to it hypersensitive, chills, rash. It worked very well for my eye pressure which went from 18 and 19 down to 9 and 10 . I wish I wasn’t allergic. Using Dorzolamide now with some sticky eyes, headaches and mild hypersensitivity. Dorzolamide is not as effective."


For Glaucoma/Intraocular Hypertension "Using Vyzulta for about a week because of high interocular pressure about 30. Had surgery to fix a dislocated Inner ocular lens, and the doctor thought I might be reacting to having steroid drops after the operation. I am experiencing pain like a small headache behind the eyes within minutes of application of the medicine. Also experiencing stuffiness and a listless feeling lately. I guess I’ll have to stay in the medicine for at least three more weeks to see if my vision improves and pressure reduces."


For Glaucoma/Intraocular Hypertension "I tried every eyedrop on the market. 1st-month on Vyzylta and my pressure dropped to a doable pressure"


For Glaucoma, Open Angle "I had been using lumigan but left eye pressure went to 24. Tried Vyzulta yesterday for the first time and had heart palpitations within one hour of using. I will discontinue and call doctor Monday."


For Glaucoma, Open Angle "Lost my vision about 90 % after use one drop before sleep like doctor says pain on my eye make worse now I am blind"


For Glaucoma/Intraocular Hypertension "After a month of use Vyzulta my eye pressure dropped from 25 to 15 . But after two months of use my eye pressure was back to 25 ."


For Glaucoma, Open Angle "Started Vyzulta 2 weeks ago. Pressure down 26 to 19. No side effects so far. Been on several drops for the past few years, this is working the best so far."

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Patient resources

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Professional resources

  • Vyzulta prescribing information
  • Latanoprostene Bunod (AHFS Monograph)

Related treatment guides

  • Glaucoma, Open Angle
  • Glaucoma/Intraocular Hypertension