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Generic Name: Xhance (fluticasone-nasal)

Xhance Reviews

For Nasal Polyps "I have suffered with nasal polyps which have recurred each time I’ve had surgery (twice). I had severe sleep issues from difficulty breathing at night, and had no sense of smell for years. I was ready to go back to surgery when a doctor prescribed Xhance 7 months ago. After 8 weeks I was improved, and now 7 months later I can smell and breathe easily through my nose. I’m so happy with the results, and avoided surgery."


For Nasal Polyps "I am 22 years old with AERD. I have severe asthma and allergies. I had surgery to remove my nasal polyps and reconstruct my sinuses when I was 18, and within a month and a half, my nasal polyps came back. It has been 7 years since I lost my sense of smell, and I have chronic congestion. My doctor put me on a course of prednisone for the past 2 weeks, and I have been on Xhance for the last week. When I say that I have not gone more than a few days without using Afrin, I have not used Afrin once in the past two weeks! I stopped sneezing, I stopped waking up in the middle of the night because I couldn't breathe, and I even have fewer asthma attacks. But most importantly, I am starting to faintly smell things! I am grateful for this medication. I will post an update when I have been on it longer."


For Nasal Polyps "I have been on Xhance for approximately 2 weeks. I have nasal polyps and allergic fungal sinusitis. I have had 3 sinus surgeries. Frequent sinus infections. Always congested. I believed I would live with this condition forever. My ENT doctor at MUSC suggested I take this Xhance nasal spray. I was reluctant, for I had taken Flonase in the past, and it had been unsuccessful. I am in disbelief how well this nasal spray has helped me. Although it has only been 2 weeks, I have seen a 98% improvement. No more sinus congestion or pressure. No more thick, green mucus coming from my sinuses. The spray doesn't sting or smell. I don't have a sore throat due to the medicine draining in my throat. I am able to sleep on both sides without issues. Life is so much better with Xhance. If you have issues, have your physician prescribe this nasal spray. I also take Zyrtec and Singulair daily. I believe I would need this for the rest of my life. But at least it works!!!!"


For Nasal Polyps "CVS substituted $900 Xhance for the $30 generic fluticasone my doctor prescribed for my allergies. They must be in collusion with the manufacturer. This product does nothing more than the generic of fluticasone except include a $870 piece of plastic that breaks and looks like a sex toy."


For Nasal Polyps "My doctor prescribed this medicine for me about 2 months ago after I tried many nasal sprays. I am completely free from congestion and very happy by the result. However, my sense of smell is not returned back yet. I am hopping that, I will be able to smell in the near future."


For Chronic Rhinosinusitis With Nasal Polyps "After seeing 2 allergists and 3 ENTs, and trying lots of various treatments, I finally got this medication, which greatly helped my nose. I went from 5 years of totally congested and drippy nose to being able to breathe through my nose (and sleep better, not choke while eating, no more mountains of tissues everywhere). However, the smell and taste I'd lost never did return, and probably the underlying problem is still there. But this lets me live a semi-normal life. I find it super easy to use, much easier than regular nose sprays. My first bottle was free, then with insurance, it was $50/month and ships to my door. No noticeable side effects, though recently my eyes have started feeling dry and some pains, but I don't know if that is related to this medication or something else (COVID? other meds? At times I also still use Azelastine nose spray for flare-ups.) But I LOVE Xhance and am so happy a doctor prescribed it and took me out of years of misery."


For Nasal Polyps "I just turned 23 and I was given Xhance for nasal polyps that made breathing through my nose very hard and took away my sense of smell. It worked well for me in the beginning with minimal side effects. I gained my smell back and I could breathe through my nose again after about a month of using it, so then I stopped using it because I got comfortable with the results. I went back to using it a month and half later once my smell started to slowly fade again and I started getting blurred vision that made me very uncomfortable. I’ve never had vision problems always 20/20. Now I am hesitant to use Xhance again because of this. Not sure what to do. Hope this review helps someone."


For Nasal Polyps "For years I have suffered from allergies and terrible swelling of sinus passages. I have tried countless other sprays, every allergy tablet on the market. My allergy specialist prescribed this and IT WORKS. This has been a game changer. We are talking quality of life changing!!!"


For Nasal Polyps "Well! May 2020, I was one of the study candidates, and everything was wonderful until January 2023. You see, I caught a URI, and my Primary Care Doctor prescribed me Azithromycin and Prednisone several times. (The only antibiotic that works for me.) Now it's July 25, 2023, and I still have a URI really bad now, and my left lung collapsed and deflated from April 28 to May 5, 2023. I've been going through nosebleeds, a runny nose, swelling of my face, headaches, blurry vision, leg weakness, toothaches, body aches, unsteadiness, confusion, white circles around lights, chills, and real bad sweating. I've been to the ER 3-4 times, only to be sent home with 'you only have sinusitis really bad.' Well, I've called the doctors/ENT that did the study and gave me Xhance and left several messages, but no answer or return of my call. Well, to end this story, my sister found out I was never supposed to have been given Azithromycin. You can't take that with Xhance due to drug interactions, and the pharmacist never caught it. I messed up. I'm still on antibiotics."


For Nasal Polyps "So far this medication is working pretty well. I had sinus surgery in December 2017 to correct a deviated septum, nasal polyps, and congestion. I've been taking Xhance for about a month now, and I've had no breathing issues except minor congestion, which is a side effect of the medicine. I don't have the seasonal allergies I normally would have this time of year. The part that you blow into became blocked (I couldn't blow into it.) after a few days of use, so I just use it like you would Flonase instead. I've gotten a nose bleed, which is also a side effect."


For Nasal Polyps "My 3rd week on Xhance and there is no change at all. I have never missed one day. Besides the fact that I don't think is doing anything, it takes few minutes to place this on the right spot so then I can blow air. I have watched videos on how to spray the medication and yet can not do it right. Why? Because you have to bend the piece the goes into your mouth in order to blow air up your nose.. I have poked my nose every time and it hurts like anything when I use it. Come on for 3 weeks?!! I would have figured out how to used it. It' s a pain in the butt."


For Nasal Polyps "My ENT put me on this about 3 months ago for Extreme sinusitis terrible allergic rhinitis and I haven’t sneezed 10 times or taken a Claritin in months!!!! This is a complete game changer... best thing ever! I am so thankful for this Xhance Spray. I read a few of the reviews and saw where someone said that their glass vial broke and where concerned about glass being sprayed up their nose. My vial was dropped last night and sad to say it did shatter but I know not to use this now and just ordered a new vial. I like the glass vial as it makes it easy to see how much product is left...although maybe they could look at a clear plastic dispenser in the future!"


For Nasal Polyps "Obscenely expensive drug with potentially terrible persistent side effects; was prescribed this after polyps returned again after surgery and budesonide regiment. It seemed to work at first; was able to breathe again after a few weeks. A little over a month later however, I woke up with bad muscle soreness and fatigue, even ran a light fever. Eight months after stopping the drug, I'm still experiencing DAILY dizziness, insomnia, muscle loss/weakness, fatigue, and hand tremors. I can no longer live my life the way I used to. This stuff royally messed me up and I've had to spend thousands of dollars on tests to try and figure out what kind of damage it did to my body (I still don't know)."


For Nasal Polyps "The device delivery system does not work like the video portrays. It simply squirts a stream into your nose that does not penetrate deep into your nose. The result is it simply runs out of your nose once you remove the device from your nostril. You might get benefit from this if it were delivered differently."


For Nasal Polyps "Xhance has greatly helped me. I am a 70-year-old female who has had allergies, sinus infections all of my life. I also have nasal polyps. For over a year, I have been suffering with constant drainage and runny nose. After using Xhance for a month, I have experienced marked improvement. My runny nose, which was so aggravating, is no longer a problem. I use sinus medication only when needed. I pay $80 a month for it, but it is well worth it."


For Nasal Polyps "While the Xhance flucanazole delivery system is indeed a plus, certain insurance plans ( medicare in particular) do not cover the cost. The average retail price for this Rx. is $475.00. While the company offers assistance to those who "can't afford the Rx.,"the reality is the average income to qualify is below the poverty line. In summary, if you're prescribed this medication, (and it is a brilliant delivery design), just make sure you can afford the cost."


For Nasal Polyps "Xhance is a joke. Wanted to charge me $600 (after insurance) for what amounts to a double spray of OTC Flonase for $15. They want over $500 for their ridiculous sprayer, which you can make from $1 worth of tubing. DON’T DO IT!"


For Nasal Polyps "Nasal polyps out of control so I asked the Doctors to allow me to try Xhance. Pressed to actuate and the canister broken cutting my fingers. Oh well I thought, but then was curious if I inhaled the glass/plastic. Curious for response. Please....this company's engineers need to spend a bit more time on "doing no harm""


For Nasal Polyps "Tried a plethora of sinus meds over the years. Xhance is the only that works!"


For Nasal Polyps "Used in conjunction with prednisone, I can finally breathe on both sides - first time in many years."


For Nasal Polyps "Xhance worked for me after 5 days."


For Nasal Polyps "An obscenely expensive delivery system for Flonase that doesn't work as well as over the counter Flonase."


For Nasal Polyps "Took Xhance for 4 days, I now have a bad headache, facial pressure, tiredness, and nausea. I feel horrible. this medicine is awful"

More about Xhance (fluticasone nasal)

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  • Drug class: nasal steroids
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Patient resources

  • Xhance Nasal Spray drug information

Other brands

Flonase, Flonase Allergy Relief, Flonase Sensimist, Veramyst

Professional resources

  • Xhance prescribing information
  • Fluticasone (EENT) (AHFS Monograph)

Other brands

Flonase, Veramyst, Ticanase

Related treatment guides

  • Chronic Rhinosinusitis With Nasal Polyps
  • Chronic Rhinosinusitis Without Nasal Polyps
  • Rhinitis