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Generic Name: Zovirax Ointment for Herpes Simplex (HSV) (acyclovir-topical)

Zovirax Ointment for Herpes Simplex (HSV) Reviews

"I've been using this product for years. It's the best thing to not having an outbreak. You must catch it on the first sign, though, when the tingling begins, if possible. After that, it will run its full course in pain at the site. I have outbreaks frequently, so I should know. I have trouble controlling when I have an outbreak. I control how I can deal with it when it comes."


"There is some confusion about the cream vs. the ointment. Chemically, acyclovir is acyclovir. The only difference between the two is only the 'CARRIER' - cream vs ointment. The ointment (for genital herpes in U.S.) has polyethylene glycol, a very slippery compound used as in laxatives and for bowel prep. It has many other medical and industrial uses. Considering the small amount possibly ingested when applying to the mouth, the only reason not to use the cheaper ointment is if you are sensitive to polyethylene glycol. The cream (oral herpes/cold sores) contains mineral oil, (also a laxative) poloxamer 407, propylene glycol, sodium lauryl sulfate, water, and white petrolatum. Proplylene glycol is supposedly good for skin, stops flaking, etc. Despite hours of research I can't find why cream is so expensive unless maker thinks we'll pay more for a treatment for our face vs genitals. The CREAM is the one that is SO OUTRAGEOUSLY EXPENSIVE!!"


"I have genital herpes as well as SLE and related complications. I mention the other health issues only because the treatment for the Lupus is to suppress the immune system, which can allow the herpes virus to become more active than it would be if my immune system was not compromised. I take valacyclovir daily for suppressive treatment, but when I do have an outbreak, I always add the acyclovir ointment. I find that it eases the discomfort and helps the sores heal a little bit faster."

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  • Acyclovir (Topical) (AHFS Monograph)

Other formulations

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Related treatment guides

  • Herpes Simplex (HSV)
  • Cold Sores