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Generic Name: Lagevrio for COVID-19 (molnupiravir)

Lagevrio for COVID-19 Reviews

"Just finished 5 days of Lagevrio taken one day after testing positive for covid. 70-year-old female, with no other health issues. The antiviral began its work after 1 day, with no more pain in the throat or headache, and heavy mucous production stopped. However, it has caused diarrhea and turbulent growling in the intestines and stomach for the last 4 days. No appetite, and only ate two muffins with little butter every day with weak tea or plain water. Kept up fluids as best I could. Little sleep at night and had to rest all 4 days, doing anything has been almost impossible. I read that once the medication is over, these symptoms will disappear so I am looking forward to tomorrow."


"64-year-old female. Had COVID 1 year ago and was very, very sick. This time, felt first symptom Monday night and tested Wednesday morning. Started Lagevrio at 8 pm, at which time I had an almost 102 fever. That broke in a couple of hours but could've been Tylenol or both. Slept well that night, getting up a few times, and on Thursday, I just felt lousy all day, coughing up some thick mucus. It's Friday now. Still feel lousy but thrilled not to be flat on my back feeling like I'm dying with a severe chest and head cold like last time. Taking 4 pills twice a day for 5 days. I've been hungry and eaten. Did get full faster. A little constipated this morning. Otherwise, no side effects that I know of."


"Started Lagevrio on day 4 of testing positive for COVID. Only symptoms of COVID were dry cough, slight fever, and extreme fatigue. Cough was starting to subside when I decided, due to my age (74), I would get a prescription for antiviral meds. My physician ordered Lagevrio. This was day 4 since testing positive. The next day, my temperature was normal, my cough was gone, my fatigue was replaced with extreme energy. I felt perfect and proceeded to work around the house! I never needed a nap, had a good appetite, and felt great all day long and into the night. I was unable to fall asleep, but continued to feel great! And symptom-free!"


"71-year-old female, also an Addisonian. Initial symptoms of COVID were nausea, felt really sick and cold for a couple of hours. This passed. Then the symptoms of a mild cold developed. I had no fever or cough, but severe lassitude and slept a lot. Tested strongly positive the next afternoon. Started Lagevrio on day 2, 87.3000 mg twice a day. Capsules easy to swallow, always with food, along with double my usual cortisone. I did not sleep well. The next morning felt worse, but a little better in the afternoon. Had a hot, red face, but this has now passed. On day 4, I felt well enough to do a little sewing and slept better. Today, day 5, I'm still testing positive for COVID, and I have mild bloating and constipation, as well as some lassitude, but I'm definitely improving. As I have a compromised immune system, I'm glad that the treatment was available, but do wonder about its long-term side effects. I've taken the risk."


"After testing positive for COVID, I was prescribed this medication. First day, I had a fever of 100.5. Swollen throat and cough. Tylenol broke the fever. My throat has cleared up. Temperature consistently normal. Loss of appetite, however, nausea and malaise. This experimental medication has a 10% chance of rebound. Glad to have finished it and hoping my appetite returns."


"Amazing med. Symptoms started Fri. Took first Molnupiravir (Lagevrio) dose Sat night. Saw relief the next morning. I was headed for a bad Covid case. My legs hurt so bad I was having trouble walking, fever, diarrhea, horrible cough, violent shaking from the chills. I am certain this med kept me from going to the hospital. The only side effect was a bad taste in my mouth and maybe fatigue. Took the 5-day course. All severe symptoms were gone."


"Lagevrio worked well and kept me from experiencing any severe symptoms of COVID. It's critically important that you obtain this drug the moment you know that you have COVID. The earlier in your illness that you take this drug, the more effective it will be. I was on Lagevrio for 5 days. The only noticeable side effect was some diarrhea. If you're on antipsychotic medication(s), your doctor will give you this drug instead of Paxlovid due to interactions. Please note that most insurance plans do not cover Lagevrio, you will need to go on Lagevrio's website and get the low-cost coupon for it. Have lots of water on hand since you have to take 4 of these pills every 12 hours."


"Was contraindicated from taking Pavlovid. Took Lagevrio as prescribed and had no adverse effects. Have suffered severe shoulder and hip pain since concluding treatment. Not sure if related to Lagevrio or not."


"This is a game changer. This literally stopped COVID in its tracks. Stopped the phlegm production hours after taking it, and by Day 2 I felt significantly better. I have asthma and have some scarring on my lungs from severe bronchitis in 2016. I received the J&J vaccine and Moderna as a booster, but did not follow up with additional vaccines due to the fact that I get sick for 5 days after taking them. I had hesitated taking it due to the fact that the efficacy rate is only 30% and that it's not FDA approved yet, but I wouldn't hesitate again. Haven't noticed any side effects and I'm usually sensitive to medication."


"This med helped a lot, it def shortened the length and the severity of my covid"


"It works well. Felt better the next day. The only side effect was severe dizziness."

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Patient resources

  • Lagevrio drug information
  • Lagevrio (Advanced Reading)

Professional resources

  • Molnupiravir monograph
  • Molnupiravir (FDA)

Related treatment guides

  • COVID-19