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Generic Name: Lioresal (baclofen)

Lioresal Reviews

For Muscle Spasm "I was taken off Soma and put on Baclofen to help with extremely painful muscle spasms that I've been told are related to my fibromyalgia. I was extremely surprised and grateful to find out that this medication, while not preventing the spasms, does stop them dead in their tracks when taken as soon as they start. I've had no noticeable side effects. A real Godsend for me."


For Muscle Spasm "I have suffered with back pain and muscle spasms for almost ten years. Sleeping through the night only happened in my dreams. Travel was limited by the necessity to stop frequently, get out and walk/stretch. A 200-mile trip could take 6 hours. Hotel beds were excruciating. After three weeks of routine dosing, my dreams are now a reality. Sleeping through the night, driving for extended periods, and staying away from home overnight have given me my life back. One word of caution, with your doctor's guidance, start with a small dose and be patient as the dose is increased. Beginning large may cause extreme sleepiness. Yep, the voice of experience. Fell asleep in mid-sentence!"


For Migraine Prevention "I have been taking it for 90 days. The medication seems to have leveled off the severity and frequency of my migraines. I take several medications, and along with this medication, it seems to be really effective. The side effects are a lot better than taking opiates or anything that makes you dizzy and ineffective. I take Topiramate, Bupropion, Amitriptyline, and Gabapentin. When a headache hits, I take a Sumatriptan and let it dissolve in my mouth."


For Spinal Spasticity "This medication, Lioresal, has been a lifesaver for me and my fibromyalgia and DDD. I have had a great experience with the medication, with only one slight side effect: it makes me a bit sleepy. Small price to pay for the fabulous benefits."


For Spinal Spasticity "It literally saved me from neck surgery. I have a disc protrusion, that bulges into my spine cord. I’ve started taking this drug and the bulge became smaller due to muscle relaxation. I can feel my fingers and have enough power in my arms again. One important thing is a withdrawal process. It takes several months to go down. Otherwise I get spasms."


For Muscle Spasm "Loss leg with riding lawn mower. Still have side effects! The leg I still have jerks and I still feel the pain of the lawn mower going over my leg. Not at all times but when they do I can't get the pain or the spasms to let up!"


For Chronic Spasticity "I have been taking baclofen for years. I changed to this medication from Soma. It has worked well ever since. I was taking 20 mg/3x a day. I have since gone down to 10mg/3x a day. Just like any other medication, I had to become adjusted to it. Afterwards, I've had no issues."


For Neuralgia "I have been taking lioresal (baclofen) 10mg 3 x per day, for 3 days now. The side effects are immense! After 20 mins I lose all sense of balance, get a major headache, and need to urinate frequently (which is difficult when lack of balance screws up walking ability!) It knocks me out for hours. Side effects last approx 6 hrs. I have cut down to twice a day now because I can't handle the side effects. Only positive is the pain eases (I have intercostal neuralgia) but not 100% pain relief- maybe 70%. I plan to visit the Dr and get off it asap."


For Alcohol Withdrawal "At 125 mg greatly helped reduce the craving but had to lower the dose due to side effects such as sleep apeneia and extreme tiredness. Currently in 60 mg . In conclusion it helped me a lot but I had severe side effects ."


For Neuralgia "I started taking this medication 5 days ago. It's 1248 am, I've been up now for an hour, sick to my stomach. I'm having a hard time when I try to lay down, my throat feels like it's swelling, unable to sleep. AND actually woke up by throwing up. And plus I'm still having a terrible muscle spasm in right lower back"


For Neuralgia "I had pains in my legs after knee surgery and I took this medicine only one pill 4 times in two days and I have never been so sick in my entire life! I was so sick to my stomach that even water made me even more sick. Whatever I ate or drank would come back up about an hour later. I could barely stand up straight, I was shaking, I had fever and chills, etc. It was horrible! I stopped taking it as soon as this started and then it took another two days to actually completely get out of my system!"


For Alcohol Withdrawal "Baclofen is a miracle for alcohol and addiction."


For Muscle Spasm "Taking 20mg per day of Baclofen for Levator Syndrome (pelvic muscle spasms). The only thing that has ever worked for this condition. No side effects that I can tell."


For Migraine Prevention "Helped tremendously with migraine and tension headaches!!!"


For Muscle Spasm "I find this medication has been great in controlling the muscle spasms I have been experiencing. However, it isn't very effective in easing the neuropathic pain I also experience."


For Muscle Spasm "Been taking these due to two back surgeries within a nine-month period. Doesn't really help with my muscle spasms."


For Muscle Spasm "I have been taking baclofen for a few months for severe spasms and it is very effective with no drowsiness."


For Hiccups "We tried it for my dad when he was having non-stop hiccups for weeks after having TIA. It definitely worked when he used the medication. It's a lot of help indeed."


For Cervical Dystonia "Baclofen has lessened the spasms and pain of my cervical dystonia. It does have side effects, but they are tolerable considering the relief I get."


For Periodic Limb Movement Disorder "On baclofen for severe pain in arms and legs. Very effective for that disorder. Must take exactly on time or pain returns right away. Side effects are headache, diarrhea and tiredness."


For Chronic Spasticity "Taken for chronic neck pain. Not only did it not help my neck pain but also triggered a migraine and made me very nauseous. It also caused drowsiness and chills."


For Cervical Dystonia "Start the medication low, slow dosage and increase as prescribed and needed"


"This has become a life saver for me. The first 2 doses caused severe headache. Since then, the results have been amazing, with no other side effects."

More about Lioresal (baclofen)

  • Check interactions
  • Compare alternatives
  • Drug images
  • Side effects
  • Dosage information
  • During pregnancy
  • Generic availability
  • Drug class: skeletal muscle relaxants
  • Breastfeeding

Patient resources

  • Lioresal advanced reading
  • Lioresal

Other brands

Fleqsuvy, Ozobax, Gablofen, Lyvispah, Ozobax DS

Professional resources

  • Lioresal prescribing information
  • Baclofen (AHFS Monograph)

Other brands

Fleqsuvy, Ozobax, Lyvispah, Ozobax DS

Other formulations

  • Lioresal Intrathecal

Related treatment guides

  • Chronic Spasticity
  • Muscle Spasm
  • Spasticity
  • Spinal Spasticity