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Generic Name: Medrol (methylprednisolone)

Medrol Reviews

For Inflammatory Conditions "This medication is very, very dangerous. I took it for only three days before I became depressed, raging, and suicidal. It is two months later and I have been in the psych ER three times, and I am still struggling and now on mood stabilizers. Before I took this medication, I was fine. Please Google 'prednisone psychiatric side-effects' before you take this medication. This should have a black box warning on it, but for reasons I don't understand, the FDA doesn't make them put one on there. It is known to cause extreme psych side-effects in up to 5% of the people who take it. Please avoid what happened to me and read before you start taking it. There are plenty of peer-reviewed clinical articles about it."


For Inflammatory Conditions "I am 58. I have been having a delayed allergy-related swelling on the right side of my face for years (5 times a year or so), I just deal with it. Finally, I decided to tell my doctor, and we are starting testing to find out what my allergy is. He gave me Medrol to reduce the swelling. Wow, swelling down in hours! I have to say I guess I have been used to aches and pains at my age... this eliminated every pain I have had. Minor things like bending to tie shoes and such. I feel like I am literally 20 years old. AMAZING. Probably will not last once I stop the medication, but man, the excellent side effects, besides treating the swelling, was a pure surprise bonus I had no idea would happen."


For Inflammatory Conditions "DO NOT take this medicine if you are prone to depression and/or anxiety! I was given the six-day 10mg dose pack for costochondritis. Everything was fine while taking it, but a few days after it ended, I began feeling like I had the flu. Then the most awful depression set in with the worst anxiety I've ever had. Insomnia too. Five weeks after finishing, it's still with me. Having to take Xanax and Zoloft now just to survive. I pray that it will go away soon and wish I had never taken this horrible drug. I'm sure it has a place, but not for those with depression or anxiety."


For Inflammatory Conditions "I’ve been on 4 mg of Medrol once a day for over ten years. Nothing else gives me the relief I need to get through the day. I’ve weaned off a few times only to go back. I’m aware of all side effects and interactions, but nothing else works for me. The day my doctor says I need to get off is the day I look for a new doctor. I have hypothyroidism and have been infected with Epstein Barr in my teens, both of which cause me widespread inflammation in my soft tissue and joints all over my body. This is my miracle medication."


For Rheumatoid Arthritis "I have rheumatoid arthritis already over 4 years from my 30 years. Medrol helps me every day to get rid of pain, but on the other side, I was now diagnosed with osteoporosis. For around 9 months, I have been taking Medrol with methotrexate 15 mg a week and Arava, and I am able to go bicycling again. Before, I couldn't."


For Asthma, acute "I appreciate this medication. It has been of great benefit in relieving my asthma distress relatively quickly. In my youth, epinephrine was the only medication for my disease, and I spent hundreds of days over the years waiting for my asthma attacks to subside. I am pleased that the extended suffering does not have to be endured now that this medication is affordable and available."


For Inflammatory Conditions "Before prescribing this medicine my doctor checked my heartbeat and said it was healthy and regular. She prescribed the 21 tablet, 6-day dose which I started the next day. The following morning (today) at 5:30 a.m. I woke up with a pounding, fast, irregular heartbeat. After doing some qigong and praying, an hour later my heart has calmed down but is still irregular."


For Inflammatory Conditions "I was given this pill for an allergy and I was only able to take the first 2 pills (4mg each) because it gave me high blood pressure so the doctor told me to stop taking it. I'm just concerned if those two pills will have any lasting side effects."


For Inflammatory Conditions "The Medrol pack is not to be afraid of. It has great benefits for a short period of time of steroids. I have terrible neck pain (Cervical Spondylosis) and am on my way to probably having surgery. But I won’t be able to do it for a few weeks. I finally asked for this steroid pack because the pain was unbearable. I took the first dose today, all six at once. It definitely has taken my pain level down from 10 to 4. I don’t know what tomorrow will bring but I have used the pack many times before, and it is always worked well. I have previously used it for sinusitis."


For Allergic Rhinitis "The use of Prednisone and Medrol together (simultaneously) causes the lungs to dry up and seriously inhibits breathing. It is a dangerous combination of drugs used for rhinitis. The use of Afrin is useless."


For Gout, Acute "Use it for knee pain with gout, arthritis,etc diagnosis with 6 to 12 months flair ups with excellent results"


For Multiple Sclerosis "Took through IV 1000 mg for 3 days I am so sick. I ache my chest hurts the side effects are terrible they're worse than the MS flare up. I would never take this again."

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Other brands

Medrol Dosepak, Solu-Medrol, Depo-Medrol, MethylPREDNISolone Dose Pack, ... +2 more

Professional resources

  • Medrol prescribing information
  • Methylprednisolone (AHFS Monograph)

Other brands

Solu-Medrol, Depo-Medrol

Related treatment guides

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