special offer

Generic Name: Norflex (orphenadrine)

Norflex Reviews

For Muscle Spasm "After experiencing a nasty bulging disc, L5/6, and diagnosed with retrolisthesis, I spent 3 years from chiro to physio, but couldn't kick the intense pain in my back which would go all over my back. At times, I'd be in bed for days. I saw a pain specialist and was given Norflex. I took 100mg once a day and after 2 days I was pain-free. I now only take it when it flares, which isn't often. It changed my life for the better."


For Muscle Spasm "Worst medicine I have ever taken. I took two 100 mg tablets, and after 2 hours, I couldn't read, focus, or swallow. I had tremors that lasted two days and severe anxiety. I felt like I was completely paralyzed, unable to lift my arms. No one warned me about the side effects, and I had no idea it could be this bad."


For Muscle Spasm "I had chronic lower back pain for several months, which was muscle-related and spread to my abdomen over time. I was prescribed Norflex. On the first day, it didn't do much. On the second day, I took it again and then, at the end of the day, had a dissociative episode and the start of anxiety, almost like a panic attack was about to kick off. I had battled anxiety for several years and weaned myself off Paroxetine nearly a decade and a half prior, so it felt like it was all coming back. I Googled after and found a side effect is... anxiety. Be careful if you are prone to this."


For Muscle Spasm "I have 2 discs that press on my spine in my neck, as well as fibromyalgia, rheumatoid arthritis & an auto-immune disease. I recently came off of Methadone & Percocet, unintentionally, when I had just enough to get to my appointment with the pain specialist I was scheduled to see for the 1st time, but he got sick & they had to reschedule me. In addition to withdrawal, my pain level kept rising, to the point that every bone & muscle in my body hurt worse than I have ever been in!!! It's the only time I've ever used '9.9' to describe my pain! I have had to go to the ER several times in the last month. I was given Norflex 2 of those times, when I had a pinched nerve. Norflex helped SO MUCH MORE than ANY of the muscle relaxers I had at home!"


For Muscle Spasm "Had a herniated disc in between my L5, S1 vertebrae and had been prescribed Percocet for 7 months. Had 3 epidural steroid injections that worked for a while but then faded away. Finally had surgery, and as a bodybuilder, had a lot of muscle in my lower back to cut through to shave the disk off of the nerve. Was prescribed Percocet still and Soma for muscle spasms and pain. All Soma did was make me pass out with little effect. Was currently changed to Norflex for the spasms, and I only take 1 pill a day, and it has done wonders without any side effects. Highly recommended for anyone with spasms or migraines."


For Muscle Spasm "I am so grateful to find something to stop the spasms in my back! The spasms were coming about every 3 minutes, much like labor pains. Painkillers were not working. Before taking Norflex, it took about a month to get through the spasms. I have been taking Norflex for the past three days and the relief is wonderful."


For Muscle Spasm "I was given this medicine for muscle spasms in the emergency room after 3 visits and 2 different hospitals. First, I received an injection of Norflex and then a prescription for 2 a day for eight days. These pills worked wonders for the muscle spasms I had been having for about 3 months. I have been pain-free for 4 months now."


For Muscle Spasm "I have spina bifida with a lot of pain. I’m a former addict, so I can’t take narcotics when the chronic pain is out of control. When I’m in bad shape, my doctor gives me two shots (IM) of 60 mg of Norflex and 60 mg of Toradol... and the two together work so well on my pain, and it lasts all day, and I can function. The sad part is I can only get these shots once every 6 weeks or so because insurance won’t pay for it, and it’s hard on your liver, I guess. But to have a combination of drugs that work so well on pain and is non-addictive... they should be used more for those who are suffering."


For Muscle Spasm "I've been suffering from various back and nerve issues for almost a year now; 2 bulging discs and sciatica. Over the holidays, I was unable to get in to see my primary care and ran out of my medications, resulting in a trip to the ER. The ER doc gave me an injection of Norflex and an Rx until I was able to get in and see my doc. It has worked amazingly well. I've had minimal side effects taking it twice daily, and within a half hour of taking it, my back spasms completely stop. It's been quite a relief."


For Muscle Spasm "I found Norflex the only medicine that helps to reduce my whiplash pain with minimal side effects. I only take one tablet in the morning on rising. It changed my life by reducing the severe pain of whiplash."


For Muscle Spasm "I find Norflex to be an amazing treatment for neck muscle spasms. I lead a pretty stressful life and every now (once every 3 months or so) and then suffer from muscle spasms in my neck and upper shoulder areas. This can be extremely painful. Sometimes, by just taking 2 tablets before I go to bed, it will cure the problem. I have never needed to take more than 3 doses to relieve the spasm. There have been occasions that I did not have any Norflex, and it will take quite a few days for the spasm to pass, even with regular massaging."


For Muscle Spasm "I was prescribed 2 100 mg tablets twice a day for muscle spasms. This is the worst experience I have ever had. Only took 2 in the morning and 1 in the evening. I was up for 3 days straight, jittery, agitated, mildly confused, and spaced out. I had no pain but could not function a normal life on Norflex. I am 120 pounds."


For Muscle Spasm "I was given this while living in the Philippines as a combo med with Acetaminophen. It worked better than any pain medicine I had ever used without the side effects of stomach upset (Ibuprofen) or fatigue, sleepiness (codeine)."


For Muscle Spasm "Very useful for stress and muscle pain. But in the beginning, a lot of side effects, due to the fact that I took 100 mg a day. (I only weigh 45 kg). Now I'm taking 1/2 every day, sometimes every two days. I feel very good, and my husband is very happy, it saved my relationship."


For Muscle Spasm "Took it to ease the pain in my jaw from clenching my jaw and grinding my teeth in my sleep. Only took 1 tablet at night. Made me sleepy but definitely helped with the jaw pain until my mouth guard was ready."


For Muscle Spasm "Took this medication for 3 days. Within 24 hours, I could not read anything, couldn't even read my watch. Pupils completely dilated, like when I took powerful drugs in my 20s. This is some scary shit. The walls and floor in my toilet were also dripping, like being on LSD, loss of balance as well. Now, day 3 stopped, taking by 9 PM, 14 hours later can sort of read again on my laptop and write this info. Does not agree with my."


For Muscle Spasm "I had a reversal ostomy yesterday. I'm currently in the hospital. I researched this medication. After it was given to me and it worked. Worked miracle for me. I can't take anything by mouth. This worked excellent"


For Muscle Spasm "Norflex is amazing for Fibromyalgia and calming your whole body. It relaxes your muscles & you feel less tension & anxiety. Really helps the pain especially in my legs, hip & back due to Fibromyalgia. Game changer!!!"


For Muscle Spasm "A pharmacist gave me brufen tablets to take during the day and Norflex at night. I took one tablet of Norflex before bed, only to wake up in the middle of the night in pain again and it felt worse. I decided to take another tablet so that I could sleep again, but two hours later I woke up with the urge to go to the bathroom. I laid there paralyzed and it felt like my brain was swimming in my skull. I couldn't even speak to warn my partner about how I was feeling. Eventually I rolled on to my side grabbing the wall next to my bed to help me get up. It's been 11 hours since I took the last pill and I am still feeling the effects of it. The effects I experienced so far with it is, dry mouth, unbalanced, confused, difficulty with speech, very sleepy and being paralyzed."


For Muscle Spasm "I have had lower back pain from a degenerated disc since my 30s caused by a fall from a horse, then the same problem in my neck from a car accident. A few years ago, I started getting what I put down to sciatica, then my right leg started collapsing on me and I have had several falls. I have strange effects to most medications, they seem to affect me differently than the norm. Norflex works perfectly on the pain side of things and generally reduces the falling. (For migraines, by the way, Relpax is amazing.) Norflex is now unavailable and I am desperate to know what to do. I am back on Palexia, but it has heaps of side effects and doesn't do the job."


For Muscle Spasm "Taking this medication was totally not for me. I have suffered anxiety all my life but it’s controlled on medication but when I was prescribed this my anxiety was next level. I’ve never felt so horrible in all my life. I was irritable, nauseous, fidgety, felt like constant panic, tense and didn’t help my condition at all. Obviously everyone is different but it’s not for me and will never take this again"


For Muscle Spasm "Worst medication I’ve ever taken. Felt like I was out of it, difficult to function or think, like coming off drugs, and it didn’t make much of a change to the spasms. I took 100mg twice a day, but stopped after 4 days."


For Muscle Spasm "I have been suffering of serious spasm in my trapezius muscles for at least 3 months, tried many products as well as home remedies. Nothing realy solved my problem, just temporary relieve from pain. Got Norflex from my local Pharmacy, took one tablet last night before bedtiime, and already I can feel a huge difference. No side effects. It looks like I have found a solution to my constant neck and upper back pains."


For Muscle Spasm "I have had tight neck and shoulder muscles with cervicogenic headaches for 25 years along with arthritis in my neck and have tried everything to ease the pain. I saw a specialist who gave me Norflex, I started on 1/2 tablet (50mg) once a day and for 7 days and my neck pain reduced dramatically and haven’t had any headaches. I then increased the dose to 1 tablet (100mg) as recommended by my Doctor, after the 3rd day I had a massive panic attack that lasted about half a day, I couldn’t stop shaking and had trouble catching my breath, I felt anxious and agitated, it was very scary and I ended up in they emergency room for a few hours. I have gone back to the 1/2 tablet and hopefully my body will adjust to the medication over time as it’s the only thing that has helped my condition."


For Muscle Spasm "I can't say it has really made any difference. However, once I started taking 1x 100mg at night and 1x 50mg in the morning. My eye sight has been affected, my hands are shaking and my anxiety is next level. I also can't focus on any daily important tasks. I have herniated disks in my back, hip and knee pain issues."

More about Norflex (orphenadrine)

  • Check interactions
  • Compare alternatives
  • Drug images
  • Latest FDA alerts (1)
  • Side effects
  • Dosage information
  • During pregnancy
  • Drug class: skeletal muscle relaxants
  • Breastfeeding

Patient resources

  • Norflex drug information
  • Norflex (Orphenadrine Injection) (Advanced Reading)

Other brands

Antiflex, Mio-Rel, Orfro, Orphenate

Professional resources

  • Norflex prescribing information
  • Orphenadrine (AHFS Monograph)

Related treatment guides

  • Muscle Spasm
  • Migraine