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Generic Name: Prodrin (acetaminophen-caffeine-isometheptene-mucate)

Prodrin Reviews

For Headache "I have used Duradrin, Midrin and Isometh which was very effective on most occasions in past for migraines. I was given samples of Prodrin and had to use it today. I woke up with the headache full blown so I didn't take it, since in the past my experience has been take it when you feel it coming on, works good. I was getting desperate, so I tried the Prodrin. IT WORKED. "


For Headache "I have tried every over the counter medicine and nothing worked. My Dr. even prescribed me 1000mg ibuprofen and that didn't work either. I got a migraine so bad that I had to be taken to the ER, after numerous tests and head scan the Dr. told me to try Prodrin. It was amazing that after only 10-15 mins of taking only 1 pill the headache was gone! I recommend that anyone who suffers from severe migraine and or tension headaches should talk to their Dr about getting this medicine. It works wonders and I personally didn't experience any side effects."


For Headache "I have had migraines since the age of 7. I am now 61. It took a lot of trial and error but Prodrin actually works at the onset. I also have trigeminal neuralgia which is excruciating nerve pain around the facial and ear area. Surprisingly the Prodrin helps stop it in its track along with an anti-seizure medicine Lamictal. That was a bonus for me."


For Headache "Suffering from migraines and tension headaches, Prodrin is a life saver. I used to take Midrin, but I couldn't get it any longer and my pharmacist recommended Prodrin. I don't know why it isn't more popular because IT really works. A side effect I get when I have sinus/allergy headaches, is it opens up my nasal passages. I hope they never stop making it."


For Headache "This works great for my migraines. Much better than Imitrex, Zomig nasal spray or Fioricet. Every once in a while, it will fail to knock out a migraine, but on the whole, it's a lot more effective than Zomig. It can make you jumpy, but faced with being jumpy or in horrifying pain, I'll take jumpy any day. If you used Midrin and it worked for you, it's worth giving it a try."

More about Prodrin (acetaminophen / caffeine / isometheptene mucate)

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  • Drug class: analgesic combinations

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Professional resources

  • Isometheptene, Caffeine, and Acetaminophen Tablets prescribing information

Related treatment guides

  • Headache