Santyl: Uses, Side Effects, Warnings, and Dosing Information

Generic Name: Santyl (collagenase-topical)

Santyl Reviews

For Keratosis "After 1 week of constant use (changed daily), I have noticed some new skin growth around the interior perimeter of the approximately 1-inch open wound that has persisted for several months on the interior of my left ankle. While there has been some reduction in the size of this extremely slow-healing wound, I would have hoped for a little more rapid improvement."


"I got Santyl as recommended by the wound care doctor. it was for scabs from deep and long gash caused by vein borrow for heart bypass. Unfortunately, I had an allergic reaction where my lips swelled up and my hands burned and itched furiously. My doctor was surprised as I was the only one to have such a reaction."


"It took a long time, but I was able to debride the black heel in about a year of use on a Type 1 diabetic's foot. No side effects."

More about Santyl (collagenase topical)

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  • Reviews (3)
  • Side effects
  • Dosage information
  • During pregnancy
  • Drug class: topical debriding agents
  • En español

Patient resources

  • Santyl drug information
  • Santyl (Advanced Reading)

Professional resources

  • Collagenase (Topical) monograph

Other brands

Collagenase Santyl

Related treatment guides

  • Keratosis

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