Generic Name: Trental (pentoxifylline)
Trental Reviews
For Intermittent Claudication "I found Trental very helpful with my leg pain. Without it, I can hardly walk. With other medicines, if I take enough painkillers, I can walk, but I can hardly stay awake. I'm afraid to drive for any distance more than 20 miles."
For Intermittent Claudication "I experienced what is described as 'blue/purple finger(s)' in my left hand. After an intensive vascular examination, this was determined to be caused by vascular spasms. After being prescribed Trental by my doctor, the blue/purple condition of my hand fingers returned to normal skin color in about two or three days. There were no noticeable side effects, and when I stopped taking the medication, the condition did not return to 'blue/purple' and to date remains a normal skin color."
For Intermittent Claudication "I have had significant leg pain for a long time. This medication took about 1-2 months to start working, but then it was great. I could run on the treadmill at much faster speeds and for much longer - when previously I'd have cramps. Also, standing stationary used to be painful after 5-10 minutes - but this also improved. The only problem is that this medication can cause anxiety and insomnia since it is derived from xanthine (chemical 'cousin' of caffeine). This is listed as a rare side effect on the drug insert, but I have heard it is more common from my doctor. I was actually given this for Peyronie's disease (off-label), but it didn't do much for that. It is supposed to inhibit TGF-beta (a cytokine) - decreasing scar tissue."
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- Drug class: miscellaneous coagulation modifiers
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Pentoxil
Professional resources
- Trental prescribing information
- Pentoxifylline (AHFS Monograph)
Related treatment guides
- Intermittent Claudication
