Generic Name: Tymlos (abaloparatide)
Tymlos Reviews
For Osteoporosis "I just took my first injection and had intense lower back pain like a spasm; it took my breath. My doctor said it was not associated with the medication. The next night wasn’t so intense and lasted a shorter period. Slight headache as well. The list of side effects doesn’t mention intense back pain. My doctor strongly suggested I continue to see if the side effects go away or become tolerable. Has anyone else experienced this?"
For Osteoporosis "I had steadily, rapidly worsening osteoporosis. Could not tolerate bisphosphonates and they did not give me any improvement. Did the full 18 months on Tymlos. I had occasional headaches and low BP but no big deal. The BMD I just had after therapy was done was great-overall 11% improvement. My lumbar especially went from -3.0 to -2.1. The injections were a drag but it was definitely worth it."
For Osteoporosis "I did my first Tymlos injection in the evening before bedtime. Within minutes, I had unbearable, excruciating lower back pain. So extreme that I sat down in a chair, screaming in pain. My partner had to call 911. I was taken to the hospital where I was monitored for several hours until the pain went away. I normally have low blood pressure. Upon arrival in the ER, it was extremely high, dangerously so from the pain the drug caused me to have. I would never do that again. My prescribing doctor insisted that I must have injured my lower back simultaneously. I certainly did not. It was the Tymlos that caused the problem. The attending ER doctor advised me to never try that drug again as I had a severe allergic reaction to it. Would mention here that I have no other known allergies."
For Osteoporosis "I've been on Tymlos for 15 months now. Broke 3 bones in a year after being on Actonel for over 10 years for Osteoporosis. Recent bone density shows 18% improvement in my hip, but lately been having lots of back pain. Doc said it's arthritis, but it's been much worse in the last few months, and I'm wondering if it's from Tymlos. Doc wants me to continue for another year, but I'm concerned. Initially had nausea when I started, and I can feel my bones being sore too. Anyone else experience symptoms this far into treatment?"
For Osteoporosis "I injected this drug Tymlos daily for 18 months. I had a bone density scan done within two weeks of starting and 6 weeks after the end of treatment. My later scan showed only a very slight improvement in my lower spine, and my scores were worse in my hip. I’m so disappointed that I did not have a significant improvement in my osteoporosis, especially since the treatment was so uncomfortable and so expensive. I just hope that I don’t develop cancer or kidney problems from using this drug."
For Osteoporosis "I used Tymlos for 3 months initially. Prior to my first injection, my blood pressure was perfect. After the injection, my BP would climb to 185-195/90-95 and the heart palpitations would start. At night, insomnia and leg cramps would arrive. My doctor took me off for one month - no heart palpitations, no insomnia, no leg cramps and blood pressure back to 115/65. My doctor asked me to start again. This time it was worse. BP even higher and heart palpitations more pronounced - extreme chest pains, as well. The leg cramps were brutal and my Achilles tendon in my left leg started hurting and burning. Eight years ago I ruptured it in TRX as a result of being on Levaquin. For seven years I have had no pain, no issues whatsoever in exercising until I restarted the Tymlos. I just went in for an MRI, the Achilles repair is intact - however, I now have damage just above - the tendon has thinned and I am on severe restrictions to avoid another rupture. I am off of Tymlos."
For Osteoporosis "I have had 5 compression fractures and 1 broken rib since 51. I'm now 55. My osteoporosis is from prednisone. I was tall at 5'9, now I am 5'4 and my organs are being crushed. I have a hunchback from repeated compression fractures. My neck is like 4 inches forward. I've lost most of my mobility. Can barely get out of a chair or bed. I can't garden anymore or do chores. No choice but to take big pharma poisons again. Taking Tymlos for 5 days now. Had no side effects until night 4, so I take it at night. I inject it into the fatty part of my thigh. On day 4, could not sleep a wink. Heart racing, whole body neuropathy, stomach pains, gas, heartburn, dizziness, leg pain. Oh joy, now this for 18 months. It better grow bone. I've read that if you get a compression fracture, you should get a kyphoplasty to stabilize the fracture, regain vertebral height, and get out of pain to avoid a hunchback. The medical field and big pharma aren't here to help, just to live in a nightmare that I cannot awake from."
For Osteoporosis "Christmas Eve 2019, I bent over and picked up a box. I fractured L4 and my spine collapsed. I did a bone density test in January and found a -3.8! It was definitely severe osteoporosis. I started Tymlos in February and have been on it for almost a year. I did another bone density test to see if it was working. I am so grateful and thankful that it's now at -2.7. I'm still on it for another year, and I know it will get even better! It works. Of course, I had side effects - headaches and a racing heart - but I'm used to it. Sometimes I still have effects, but not always. The only downside is the side effects, but it has worked!"
For Osteoporosis "I used Tymlos from Mar 22 to Feb 23. From the first injection, I experienced a rapid heart rate, dull aching in my mid-back kidney area, frequent urination, and some dizziness. I used it before bed due to the side effects. If I got up at night, I was often disoriented. The injections also sometimes caused bruising and pain. After 2 months, I began using it every other day due to the side effects, even though these were primarily at night. But I was really tired due to getting up at night to use the bathroom. I was optimistic about this drug as it is designed to grow bone, rather than just stop bone loss like biophosphonates, and I was willing to continue treatment for another year. Super disappointed with my DEXA bone scan results and stopped Tymlos due to essentially zero benefits: Hip: -2.9. Prior -2.8, slight decrease; Femoral neck: -3.4. Prior -2.9, major decrease; Lumbar spine: -2.2. Prior -2.2, no change. For me, Tymlos was not effective. Blessings on the journey toward stronger bones."
For Osteoporosis "My first week on Tymlos was excruciating! About five minutes after taking the injection, I had heart palpitations, a severe headache, my teeth hurt so bad, and then the lower back spasms started and I cried out in pain. It was horrible. I called my prescribing doctor after the first couple of days, and she said that she had never heard of anyone having the side effects I described. They made me feel like I was crazy for saying that it was so horrible. I have now suffered through a little over a month of this drug. Although not so intense, I still have heart palpitations and now severe thigh and feet cramps. I feel terrible and don't know how much more of this I can take. I am 59 years old and I work full time and am a very busy person, and this has made my quality of life very bad. I hope it is worth it!"
For Osteoporosis "I used Tymlos for approximately four months. After the first month and a half to two months, I started having really bad leg and back pain. The nurse practitioner convinced me to keep taking it, so I continued for another month and a half. However, the pain became unbearable, and I had to go to the emergency room. I was told that I was growing new bone in my legs, causing the pain to feel like growing pains. Despite this being the only side effect I experienced, the pain was so severe that I had to stop taking it as I couldn't endure it anymore, I was up every night."
For Osteoporosis "I had Tymlos and got side effects of an instant headache, racing of heart, and spinning. Headache is a pressure headache and it lasts for hours. This is day in and day out. I have been on Tymlos for 4 weeks, and it’s just the same thing every night. I can’t sleep. I tried it this morning to see if it makes a difference and it ruined my day. I am having surgery on my back in 3 months, so it’s essential... but I don’t know if I can take it much longer. It’s wrecking my quality of life."
For Osteoporosis "I wanted to update my experience. Now after having been on Tymlos for 2 weeks, I am happy to report the side effects disappeared after the first week. I also injected on alternate days for the 1st week which helped a lot. Injecting before bed was a big mistake for an insomniac like me. Just made me focus on my elevated pulse. I find injecting just before I exercise works great."
For Osteoporosis "I am 77 and my bone results just get worse each time. First injection of Tymlos on 7-23-20. Two hours later, a low-grade fever. Next night, the same thing. Third night, didn't inject and no fever. I cannot take this drug and told my doctor that."
For Osteoporosis "I am 72 and in an osteopenia stage and had multiple fractures. Forteo gave me too many side effects. Therefore, I have been taking Tymlos for 10 months. Compared to Forteo, Tymlos has been tolerable. The only negatives have been my high calcium score and joint stiffness. Because of the high calcium, my dosage has been reduced to 40 mcg every other day. Has anyone experienced this crippling stiffness?"
For Osteoporosis "After the 1st injection, I had back and leg pain, headache, and heart pounding. The headache lasted about 20 hours along with an ill feeling. The next 2 injections, the back and leg pain were much less, but still the headache and slightly ill feeling. Now 8 days in, just slight pain and occasional heart pounding, but only for a short period of time."
For Osteoporosis "Did not do well on Tymlos. High 24 hr. urine Ca. scores - hypercalciuria. Started Tymlos June 2019, stopped April 11, 2020. Other issues: cramps in legs, mental fog starting second month, joint pain in hands, tiredness on a daily basis. Got new rheumatologist, second opinion. Started Prolia today. Should have monitored bone markers more carefully both before and during treatment of Tymlos. Now I know. New doc. will do blood tests and urine every 3 months. Tymlos not for me."
For Osteoporosis "I have been on Tymlos for a month and a half. The only side effect I’ve noticed is that after some injections my heart races for a bit. Not every time. Sometimes upper stomach pain but rarely. I really hope it makes my bones stronger. I’m willing to stay with this for eighteen months if it builds my bones."
For Osteoporosis "I was apprehensive about taking this Tymlos injection because I’m always sensitive to medications. I took the shot Thursday night at 9:15, immediately had lightheadedness and fatigue, heart palpitations. The heart palpitations went away, lightheadedness and fatigue stayed. I went to bed at 11 PM, was awakened by horrible reflux at 3 AM. Fell back to sleep, was awakened at 5 AM, severe pain in my entire head, teeth, gums, etc. Sat up to get Tylenol and was totally blind in my left eye. I woke my husband, he took me to the emergency room. Spent 7 hours being tested, 2 CT scans, expert eye examinations, neurological testing, blood tests, all normal tests. I try never to take pain medication because it makes me nauseous, but they said it would be baby doses. Ok. Well, wound up dry heaving for 3 hrs. Finally released, went home. Once pain meds wore off, pain in head started again. I took 2 gabapentins, 2 Xanax, and slept all night. I woke up Saturday morning, same pain in head, the pain jumps all around."
For Osteoporosis "I have been on Fosamax (awful side effects) and Reclast (awful side effects). I started Tymlos 18 months ago. I was only dizzy for about a week, but then side effects stopped. I injected once a night into my stomach. No compression fractures the whole 18 months!!!! First time in 6 years! Previously, before this med, I had 5 compression fractures and 1 broken rib. Before I started Tymlos, my Dexa scan was -3.4 osteoporosis, and after Tymlos, down to osteopenia stage. I had a 16 percent increase in spine and 12 percent in hip!!!! This Tymlos works!!!! But now I'm on Prolia and it is poison! I want my Tymlos back. I want to take it longer because it works!!!! Of course, something that actually works, and you can only take it for 18 months. I say rubbish!"
For Osteoporosis "I started Tymlos on 3/12/20 and decided to discontinue it due to heart palpitations and anxiety. I also had terrible insomnia with it. I took the injection at night before bed, but when I tried taking the injection in the morning, I would have to lie down because it made me so tired (go figure). With all of the COVID-19 worries, I sure don't need my heart racing any more than it already is. Also, the black box warning of osteosarcoma worries me a lot, frankly."
For Osteoporosis "Tymlos is the worst drug ever. Took it for a little over 2 months. Extreme nausea almost immediately every day. Migraine every day. Daily, between 3 and 4 PM, every joint ached so bad I had to lay down. Constantly felt like I had the flu. Or like I was on chemo. I have been off of it for over 2 months yet still have symptoms that I didn't have before taking it. I am afraid permanent damage has been done. Going to try a tablet next. This medication should be taken off the market. Oh wait, big pharma doesn't care about you, it's all about that dollar."
For Osteoporosis "I found out I had a T-score of 3.5 at age 55. They told me I have osteoporosis in my spine. I’ve been using Tymlos for almost two months. The first time I used it, I had what others mentioned: pain in the back. It was very intense. I tried it the following day, and it didn’t cause the same pain. Each day following was fine. I have minor back pain after each injection, but use a heating pad to relax it. It is bearable. I’ve heard such good results, so I’m looking forward to having a bone density scan after 18 months that I’m supposed to be on it."
For Osteoporosis "So I have been on Tymlos, and I agree with others commenting on the severe back pain! But why? I haven’t found an answer. Also, extreme dizziness. Like nothing I have experienced. All the time, not just after the shot. I’ve been taking it for 5 months. Not sure I can do it for the 2 years the doctor wants me to."
For Osteoporosis "I've been on Tymlos for only 1 month. I had a spinal fracture in the past, as well as multiple other fractures from falling from a standing position. Anyway, I have back pain from fractures, but the back pain on Tymlos was so severe that I have stopped it. I had a headache after the injection, so I just took Tylenol. Fatigue was another problem, along with nausea. I took Zofran. I will ask my doctor to try Prolia. Oh, I am 69, diagnosed at 50 with osteoporosis, but was always afraid of side effects. Good luck."
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