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Generic Name: Alphagan P (brimonidine-ophthalmic)

Alphagan P Reviews

For Glaucoma, Open Angle "Unfortunately, the drug was not very effective for me. I experienced side effects, such as eye irritation, itchy eyes, minor swelling, and minor blistering. This medicine did not reduce my eye pressure."


For Glaucoma, Open Angle "Horrible, like all the rest I have tried. Same effects as others, intolerable burning, beet red eyes, itching, blurring, rapid heartbeat, swollen upper eyelids, pouches and discoloration below eyes, loss of hair and eyelashes,on and on. Embarrassing to appear in public. People assume I am either an old lush or smoking too much pot. Not to mention my bald spots. You need to update your responses, what occurred in 2016 may be different than 2022. I think we need to band together and fight the big pharmas. Many $ for eye drops that are toxic to your system? One prescription cost $500 for 2 month supply. I had to discard it. My skin burned like fire. I have gone through this list of drops and not one is safe to use. S.O.S. someone help us!!!!!!"


For Glaucoma, Open Angle "I have been on Alphagan P 0.1% for about 18 months now (there were gaps when my doctor had me try different eye drops - all in the prostaglandin family, which all bothered me a lot). Alphagan (Brimonidine is the generic version) suits me pretty well. I have Normal Tension Glaucoma, before I started on eye drops, my IOP was 15, with treatment, it is down by 1/3rd to 10. The whites of my eyes have some redness and irritation, but nothing like I felt when I tried Xalatan (latanoprost) or Zioptan. I am very careful after I use the drops to rinse my mouth out thoroughly & even gargle, then I also gently rinse my eyelids and lashes with cool water. I do plug the inner corners of my eyes after dosing for 3 minutes to prevent the medication from getting into my sinuses or throat. I prefer the Alphagan P brand name over the generic because the 'P' stands for Purite, which is a much less harmful preservative formula. Allergies to Brimonidine are fairly common, so this drug may not be for everyone."


For Glaucoma, Open Angle "I have open-angle glaucoma in both eyes. Alphagan P brought my pressure down in a short length of time. The pressure has stayed at acceptable levels for the past twelve years. I have not had any side effects."


For Glaucoma, Open Angle "I have been diagnosed with open-angle glaucoma this week. I've been on this medication for 3 days and have no side effects at all. I've had other drops (used for other issues, not glaucoma) that burned, and stung, but not this one. I'll have to wait a few weeks to see if it brought the pressure down when they check my pressure. Fingers crossed."


For Glaucoma, Open Angle "On the Alphagan-P 0.1% morning and evening for 11 months. They are the first ones out of 4 brands that do help with my dry eyes from many hours of daily computer work. I do have a terrible dry mouth side effect, even a dry nose and throat to some degree. The redness in my eyes lowered though. I have a blood pressure of 110/70 and Alphagan-P lowered it down to 50. I could not function in the first week. I could not walk without falling aside. This went away after 7 days or so. My IOP keeps going up over and over again, I even had SLT in 2020 on both eyes and another one on the now glaucoma affected eye in 2023 again. Nothing helps and the blindness in this eye keeps progressing now. It is very sad that one has to start with the China or India made Latanoprost to begin a health insurance coverage. These drops resulted in terrible itching and blurring. I had good vision in 2017, no loss of sight due to glaucoma at all and my IOP used to be 16 to 18. I started losing vision in one eye the next year together with IOP up to 24."


For Glaucoma, Open Angle "Very strong side effects for me. I experienced blurred vision, dizziness, and fatigue to the extent that I cannot maintain my normal daily activities."


For Glaucoma, Open Angle "Became ineffective within six months and developed an allergic irritance with it."

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Patient resources

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Other brands

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Professional resources

  • Alphagan P prescribing information
  • Brimonidine (EENT) (AHFS Monograph)

Related treatment guides

  • Glaucoma, Open Angle
  • Intraocular Hypertension