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Generic Name: Cortisporin Otic (hydrocortisone-neomycin-polymyxin-b-otic)

Cortisporin Otic Reviews

For Otitis Externa "In September 2021 I had a lot of itching and burning in my right outer ear canal. It felt like a zit in my ear canal. My ear canal began to get inflamed and wasn't improving, so I went to urgent care. The PA looked in my ear and said my "eardrum looked inflamed." She prescribed these otic antibiotic/steroid drops. They instantly caused more itching and burning in my ear, and I noticed that it was drying up in my ear. I now had tinnitus and a feeling of pressure and muffled hearing. My ear canal began to swell up. After FOUR days of this I did some research and found a lot of reviews on another site where people had increased pain and itching, and loss of hearing and tinnitus. Something most reviews have in common is that people found out their blocked hearing and itching and pain was being caused by this medication drying up on their eardrum and forming a cast. The cast keeps the eardrum from vibrating, which decreases hearing and caused a muffled or blocked sound in the ear. Don't use."


For Middle Ear Infections "My 7 year old son had ANOTHER ear infection. The minute I tried this new medication he started cry and rubbing his hear crying out in pain. His ear turned bright red and he got a terrible taste in his mouth. I obviously stopped giving it to him. This is the first ear drop that's caused this reaction from him."


For Otitis Externa "I had a HORRIBLE allergic reaction to the ear drops! The medication made my look like I had a chemical burn on the right side of my face and blister like on my ear. The itching was immune to Benadryl and I am hoping my face will heal soon."

More about Cortisporin Otic (hydrocortisone / neomycin / polymyxin b otic)

  • Check interactions
  • Compare alternatives
  • Side effects
  • Dosage information
  • During pregnancy
  • Drug class: otic steroids with anti-infectives

Patient resources

  • Cortisporin Otic drug information
  • Cortisporin (Neomycin, polymyxin b, and hydrocortisone Otic) (Advanced Reading)
  • Cortisporin (Neomycin, Polymyxin B, and Hydrocortisone Otic Solution)

Other brands

Pediotic, Cortomycin, Casporyn HC, Cort-Biotic, Oti-Sone

Professional resources

  • Cortisporin Otic Suspension prescribing information

Other brands

Casporyn HC

Related treatment guides

  • Otitis Externa
  • Middle Ear Infections