Estradiol Patch for Postmenopausal Symptoms: Uses, Side Effects, Warnings, and Dosing Information

Generic Name: Estradiol Patch for Postmenopausal Symptoms (estradiol)

Estradiol Patch for Postmenopausal Symptoms Reviews

"This medication saved my life... I actually like the Mylan better than the Vivelle as far as the way I feel. The Vivelle caused sinus problems and gassy bloat. The Mylan product did not do that to me. However, the Mylan product doesn't stick as well or last as long... OVERALL: I love estrogen replacement, and it is a TRAGEDY that women are suffering, and their docs are not offering HRT when it is now proven that HRT prolongs life and has a protective influence on heart, bones, and brain. I want to tell every woman out there, do not be a hero, do not suffer, and do not be afraid. Estrogen is good for you and can give you your life back. Why do none of the women I talk to know this? Crime!!"


"So first, the information is outdated on the risks and more than likely based off of the WHI study which ended up not being accurate. So please find a good doctor who is knowledgeable. Second, I use patch 0.75 for perimenopause. I change it every three days, so if it’s not working for you, make sure you have a high enough dose. Make sure you’re also using progesterone if you have a uterus, and make sure you give yourself at least 8 weeks for your system to adjust. If it’s not sticking, switch brands and require they fill that brand. I have learned that changing in the morning before my shower, wiping the area with alcohol, and then drying on a low setting of a hairdryer, then sticking it on. Yes, you’ll get the ring around, but to me that’s whatever if it makes me feel better. You can try a tagaderm patch over, just slightly bigger than the estrogen patch. And there will always be negative reviews first. I want women to have a positive review that doesn’t terrify them."


"I used Vivelle patch for years until it was discontinued. Then, with research, I found that Estradiol by SANDOZ is a generic for Vivelle. I use the 0.05 mg every 4 days and I am pleased. I apply the patch at night and take my shower in the morning, and have never had one fall off. I am 77 years old now, and I have been using it since I turned 50. My Medicare D has never covered it, so I use a coupon and pay around $78.00 for 3 boxes of 8 patches. I am healthy, take no other medications, my weight is good, and my skin gets compliments on looking healthy. That is my personal experience, I hope it helps someone. PS: This HRT helps me sleep well."


"The Sandoz brand estradiol patch is absolute garbage. It stops working for me after about 6-8 hours, and it's supposed to last 7 days. My gyn told me to prep skin with acetone (!!!) and to dry skin with hair dryer then apply patch and hold 10 seconds. Women deserve better than this rubbish - in all forms, from having to apply acetone to skin, to patches that don't live up to what they're supposed to do."


"I've been using these patches for several years now. They work much better than the pills did. Once in a great while I would have one unstick a day or 2 early, so I would just replace it with the next one in the box. But due to the pandemic, I got a 3-month supply, and they are drastically not sticking (even after 4 days), and I am short 2 weeks before my insurance is willing to refill my script again. And my last one completely fell off this morning! Mylan needs to get a better adhesive for these. (I would give the drug a 10 rating if it stayed on)"


"I suffered premature ovarian failure where my hormones fell off a cliff; hot flashes, night sweats, migraines, mood changes. I was prescribed 0.0375 mg patches 2x week (along with a low dose progesterone pill to balance), and the Sandoz brand filled by my pharmacy worked wonders right away. I’ve used it now for 8 years, been very comfortable on it, have regular screenings that are good. I’ve never once had a patch come off (and I’m a swimmer). The pharmacy filled once with Grove Pharmaceuticals brand and my skin got very dry and irritated, so I asked to fill again with Sandoz. My insurance doesn’t cover prescriptions, and patches are pricey, but coupons cuts the price by more than 65% and pharmacy always accepts them (just pulled up on my phone). Hope someone finds this helpful, and best wishes."


"Following up on my August 5, 2020, review of the Sandoz patch. My gyn switched me to a twice-weekly patch - Mylan. This brand is worse than Sandoz. I applied a patch Friday night, and by Saturday evening, I was sweating profusely. This is the second week on the Mylan patches. Again, women deserve better than being guinea pigs for cheap drug companies."


"Used Sandoz brand for the first 8 Estradiol patches. No problem. Pharmacy switched to Mylan, a horrible experience. I use twice a week. After the first 2 days, it starts to itch and turn red. Burning sensation by day 3, and it's hard to remove and leaves deep red burn marks and continues to itch for a week. Marks remain on my body for over a month now. Not recommended!"


"Absolutely AWFUL!! I have been prescribed Estradiol Patches made by Sandoz, and I am supposed to keep it on for a week. I maxed out at 6 1/2 HOURS... they are truly worse than generic cartoon Band-Aids that are overpriced & don't stick! How in the world did these ever pass quality control from the FDA?! A total rip-off!! I clean with alcohol, let air dry, used tape, and they still come off. ANY amount of perspiration will make them bubble right off. Sorry, but we all perspire EVERY SINGLE DAY! How was that little tidbit overlooked?"


"I’ve used lots of different patches over the years. My favorites have been the Vivelle Dot and the Sandoz patch. The Mylan estradiol patch is worthless - you’re supposed to wear it a week, but it only stays on lasts a day or two, it smells, and it causes skin irritation. Unfortunately, it’s the only one that I know that my insurance will pay for. I’ve been using Sandoz, but have to pay $65 a month for it. Does anybody have a suggestion on a patch estrogen that Priority Health pays for?"


"I was put on the Minivelle patch several years ago. It worked great. A year ago, my pharmacy changed to this estradiol patch made by Mylan. I didn't notice until I used it. The patch does not stay on, but the worst part is what it does to my skin. I have horrid red patches that hurt and itch, and they do not go away. Now I am having trouble finding a place to place the patch because I am covered in the scars from using this brand. I use CVS Pharmacy. They told me they cannot get the patch, which is why they switched to Mylan. I am contacting Noven to see what is going on. I see my doctor next month. I cannot continue using this product. It is horrible."


"Sandoz patch... I don't find it effective at all. If I use the whole patch, it's like someone gave me speed for about 4-5 hours, I had a super racy heart, super wound up, then... nothing. The speedy feeling has made me remove the patch. I cut the 0.5 patch in half. It doesn't feel like it's doing anything particularly. Why does the US not sell Estradot? It is made in the US! Oh, and what is it with the permanent red marks???? Take a patch off and there's a red mark that is taking weeks and weeks to go away (if it does at all). It's like it's been tattooed to my skin. In 18 months of Estradot, I never had that problem. I never had a sticking problem or a tolerance problem, just an acquiring problem - which again, is completely idiotic. The boxes I got were labeled right on them 'made in the USA,' but they're sold in Australia. Why can't I get a US-made medication in the actual US??????? And why does it cost me a third to buy it elsewhere than any of these US acquirable patches cost?????"


"I just started using the Mylan Estradiol patch after using the gel. I wanted to try something more user-friendly than the gel, though the gel worked well. I have had the same terrible skin reactions to the patch as I’ve seen commented on this site. I called Mylan to file a product complaint and plan to do so with the FDA as well. I will ask my doctor to write for another type of patch."


"I absolutely can't stand the Mylan brand Estradiol patch. For 3 years, I have been using the Sandoz brand and loved it. No issues. In January, when I picked my patches up, I realized the brand was different... okay, no big deal is what I told myself. A patch is a patch, right? Well, it makes a difference. The Mylan comes off in 2-3 days, and I am having to use Tegaderm to keep it on. Then the awful rash that is still on my skin after being off for 4 weeks now. I have searched high and low for Sandoz, and no one carries it anymore. What is a person to do?"


"This refers to the Mylan estradiol twice weekly patches. After 16 comfortable years using Vivelle Dot estradiol patches, I was supplied by Express Scripts with the new, supposedly 'generic' Mylan estradiol transdermal dot patches in the same strength, 0.025 mg. During the 4 1/2 weeks I used the Mylan product, I developed hot flashes, night sweats, brain fog, and urinary tract infections. I could not understand what was wrong until I recalled that my symptoms began when I started the Mylan product. I found out that Vivelle Dots are still under patent. Mylan patented its own competing transdermal patch in order not to infringe the Novertis patent. It is NOT the same product. A return to Vivelle Dots solved my problem."


"I have used the estradiol patch but will probably have to change to something else. I initially did fine and was happy with the patch. However, this past month, something has changed. The patch areas have become itchy, red, and irritated. I called my healthcare provider, she is also on the same patch and has experienced the same issue this past month. Obviously, the Mylan company has changed something...adhesive? Something that isn’t working. I made a call to customer service, and they didn’t seem too concerned. Houston...we have a problem. Mylan...fess up to what changes you made and fix it!"


"I have been on the estradiol patch (Vivelle) for three weeks, and I feel like a new woman! Gone are the hot flashes, night sweats, and brain fog. Hello energy, I've missed you immensely! I also take 100 mg progesterone at bedtime. This combo is a game-changer! Just wondering why I didn't pursue it sooner."


"I was caught in a vicious cycle of soaking wet hot flash after soaking wet hot flash, which caused me to become agitated, which caused my heart to race ALL NIGHT LONG, which then caused me to be irritable, and I could barely focus during the day. My doctor started me on the estradiol patch 0.05 mg, and within a few days, I felt like a new person. I now go through the entire night with maybe one minor hot flash, and the resulting anxiety is gone. I sleep now better than I ever have. The only side effect I have noticed is that my breasts are a little tender, but not enough to make me stop. If I wind up gaining a few pounds, who cares, I am a human being again."


"I used to use Climara. Great option. After I changed insurance, I had to use a Mexican brand that worked really well. After I moved to another state, I had to get a US brand. I was given Mylan Estradiol patches, and after 2 days or less, they fall off. I just feel I wasted my money, and they are not cheap."


"Mylan Estradiol Patch 1.0 seems to be ineffective! Suffering from menopausal symptoms due to a complete hysterectomy. Booted off the good stuff... Minivelle. Due to change of insurance, even though I have full coverage! Insurance won’t pay the $450 cost for a 3-month supply. I wonder what’s even on the Mylan Estradiol Patch, is it even real?"


"Sandoz Estradiol Patch does not stick. It does not peel, instead, the entire patch comes loose at once. I get 2 days, maybe 3 days out of a patch. Do not accept Sandoz brand from your pharmacy, you will be wasting your money."


"I had the Sandoz patch, and it was great - a nice, thin patch that I forget is there except that I feel much better. The next month, I got the Mylan patch that is covered by my provider. It is thicker and catches just a little bit on the edges. More importantly, it leaves red marks underneath upon removing it and small marks that look like burns around the edge. I've also seemed to have some itching around the patch while it is on. I will be switching back to Sandoz."


"This patch is so frustrating. It only stays on a couple of days because the material it is made of allows the water to soak in when you shower. Then the skin stays wet underneath and starts smelling sour. The adhesive on the edges irritates my skin and causes itching. What good is it if I can only get about 3 days out of it? I used to use a thinner patch made out of a different material, and I never could tell I even had it on, but the company quit producing it."


"My biggest concern is that I am not getting the relief of post-menopause even though I am using a 0.1 mg patch because the patch does not stay on my skin. I have been using the estradiol patch for many years. I was using Vivelle Dot until it was not covered by my insurance and switched to Mylan Labs. It would be nice if these patches could stay on my skin to rate the effectiveness of the medication."


"I am in perimenopause and started having horrible hot flashes 4 months ago. 10 a day at least. Crazy fluctuations between hot flashes and cold chills and shivering. Night sweats at night. Was miserable. Finally found a GYN who is current with the research and she prescribed the patch and progesterone pills. She initially prescribed a brand name 2x a week 0.05 patch. Well the manufacturers are all discontinuing making the brand name patch because the patent is up and insurance will only pay for generic. Furthermore, there is a patch shortage nationwide, so there was only one generic available - Mylan. I Googled and read not so pleasant things and was super freaked out but had no other options, so I tried it. After one week, I noticed I had fewer hot flashes. After 2 weeks, I had ZERO hot flashes. OMG, what a relief. It’s wonderful not to have crazy temperature changes all day and night. Yes, it irritates my skin, but the patch has a lot fewer risks than pills, so it's okay."

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