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Generic Name: Nexletol for High Cholesterol (bempedoic-acid)

Nexletol for High Cholesterol Reviews

"After trying everything on the market to lower my cholesterol, and experiencing terrible side effects from statins, I read about Bempedoic Acid. I was already taking Zetia with no results. I asked my cardiologist about this new drug, Nexletol, and he agreed to let me try it. In three months, my total cholesterol went from 255 to 126 and no side effects! It worked for me when everything else did not."


"I am taking Nexletol for high cholesterol. It was the first medication that did not produce dizziness and leg cramping (caused by statin medication). Downside: expensive, occasional leg cramping and chest tightness."


"After taking Nexletol for 1 1/2 years, I developed severe peripheral nerve pain in my arms, shoulders, legs, and feet. I had severe burning pain. After stopping Nexletol, the burning in my shoulders started to lessen after 3 days and quickly stopped. However, the stiffness in my back, and the burning nerve pain in my legs and feet has taken over the last 1 1/2 years to get better. It’s been a slow process. (Gabapentin, PT, Tylenol, NSAIDs, and cortisone injections). I am now treating IT Band issues and bursitis. By the way, I had similar peripheral nerve damage from statins previously before taking Nexletol. That nerve pain wasn’t as severe though. On a good note, Nexletol alone decreased my cholesterol greatly."


"Leg pain when I start walking. Drowsiness. Back pain. Frequent urination. Tiredness."

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Professional resources

  • Nexletol prescribing information
  • Bempedoic Acid (AHFS Monograph)

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