Generic Name: Vasculera (diosmiplex)
For Dietary Supplementation "As a recent Stage 3 cancer patient, I was very alarmed that there is a warning NOT EVER to use this drug - something my doctor certainly did not make me aware of, so I stopped immediately upon learning of it. I have no idea what this drug is supposed to do - I took it for two weeks for venous ulcers and noticed no improvement. Also, I find it bizarre that it costs insurance companies $3000 a month, but you can buy it direct for $35. Sounds like a scam, doesn't it."
For Dietary Supplementation "I had a blood clot in my femoral vein in my right leg. I was left with a leg that had become extremely painful and swollen well after my recovery. I was on blood thinner for a period of three years to keep the swelling and tired feeling somewhat under control. I went to a vein clinic in Memphis, TN, to see if there was anything I could do to get relief. He took me off of my blood thinner and asked if anyone had talked to me about Vasculera. The doctor explained that the cost is expensive (about $1800/month), but if my insurance rejected it, he would see what he could do through a Transition pharmacy. My insurance rejected it. However, he got me a prescription for $117 for a three-month supply. Results have been amazing. Before, I had to wear a compression sleeve and had worn it continuously for 3 years. IT IS NO LONGER NECESSARY! My swelling and pain have become minimal, and the heaviness feeling has become a non-issue. This has been a life changer for me."
For Dietary Supplementation "Diagnosed with mild chronic venous insufficiency (CVI). Started with Vasculera, continued for 3 months. Started having stinging sensations throughout body. Been off the drug for approximately 6 weeks, and the pain has gotten better. Still having some issues, such as stinging and muscle pain. It is getting better, but never had these issues until started on Vasculera."
For Dietary Supplementation "Started using Vasculera, and within 3 weeks had severe leg pain; poor flexibility and pain in ankles. Had to use my cane in the morning. Have stopped for about 1 week, and symptoms are improving daily... no cane necessary."
For Dietary Supplementation "The supplement has no discernible effect on my venous hypertension in the leg. I find it reprehensible that: 1. The information on what it does and how it does it is non-existent. 2. The fact that one should not use it if you've had cancer! That applies to a lot of people. Many are using it with no idea this is the case!"
For Dietary Supplementation "The NP with my rheumatologist prescribed this a year ago. She had a bunch of samples she gave me, so I didn't pay for them. I've been taking them, but my legs, ankles, and feet have been swelling. I just stopped this as I'm not sure if it's due to the Vasculera or not. I've since changed rheumatologists and see that one this next week. I need to find out why I'm having edema. My labs are fine."
For Dietary Supplementation "I have taken this for 8 months now! My venous reflux never caused me any pain. I would say mild discomfort, mainly due to swelling. The fact that it is a food based drug, was very appealing to me. And I feel it works very well for me."
For Dietary Supplementation "Slight relief but stuck with it per Vascular Dr. Started noticing: brittle nails, dry skin, and intermittent stomach pain. Primary doctor didn’t think the product was cause so I kept taking it. I started having dizziness and a general un-well feeling. Prior to knee surgery 07/22 the PA in surgeon's office stopped Vasculera and found in research that Diosmin (and perhaps “proprietary” ingredients) cause stomach issues along with other things. Within a week of stopping Vasculara most symptoms resolved. My stomach issues/dizziness have gone, I have fingernails for the first time in 2 + years after being off of Vasculara 3+months, and my skin and hair getting back to normal. I have learned there are limited studies in France on this supplement that are not officially published. Be cautious and look for side effects. Expensive. When I called to stop prescription due to symptoms, the company quickly refunded the last mailing and did not want one bit of information about side effects. Company interaction left me with questions/doubts."
For Dietary Supplementation "I have only started taking this medication. I have severe Chronic Venous Insufficiency. I am having removal of the incompetent veins, but am hoping I can have improvement in my remaining vessel structure with this medication and reduce the current inflammation."
For Dietary Supplementation "Three months ago I was diagnosed with Lymphedema, after two doses the swelling in my legs is completely under control. More than 90 days on this medication I have had no discernible side effects. Would like to know why a 'dietary supplement' is so pricey."
For Dietary Supplementation "I just started taking this medication and I hope it helps with the edema I am having. I will update how you does for me in about a month to give it a chance to work. Additionally I will be having a procedure in late Aug. or early Sept. to correct the leaks in my left saphenofemoral junction and great veins"
For Dietary Supplementation "I have been taking this product since 2017 with great results. Because of severe venous insufficiency due to an earlier fractured ankle. I took Vasculera for 8 months - samples supplied by vascular surgeon's office. Because of the cost, I started after that to use otc Diosmin capsules per physician recommendation. The pain and itching I experienced before is gone. I also wear compression stockings per physician suggestion."
For Dietary Supplementation "I have used this for about 5 years. My consent leg pain is so much better. I thankful to my Dr for helping me. It has helped me so much. I get mine for 117 for 3 months. I have CVD . I have really been helped by this drug."
For Dietary Supplementation "Within one week of taking vasculera I noticed a visible and palpable difference in the amount of swelling in my legs. I use all the standard complete decongestive therapies as well as many complementary therapies like acupuncture and massage. But I always hit a wall with all of them were their effectiveness plateaus. But after starting vasculera, my legs are less heavy, smaller, less blue/ purple, and I hope to see an improvement in my spider veins as I continue. No side effects, which I was surprised by, considering it can cause GI upset and I have IBD. I love that it’s a food grade vitamin medicine and feel better about taking it than an alternative like lasix"
For Dietary Supplementation "Does not seem to alleviate pain after having vein procedure. Very expensive and Ibuprofen 600 mg seems to work better and is much cheaper. I would not buy this again because of the lack of results. I feel like I was forced to take it by the vein doctor. I wonder if they get kicked back from it."
For Dietary Supplementation "Severe leg pain in back of most swollen leg. Pain in calf, ankles and thigh. The pain would wake me at night. Pain with stiffness. Sometimes it moves and radiated toward the ankle or towards the knee. Caused severe leg cramps as well. Took twice a day and tried once a day but symptoms stopped when I stopped medication."
For Dietary Supplementation "I was prescribed Vasculera, by my Vascular doctor. I started taking it in 2019. In 2021, my legs and feet looked amazing, and it really help. However, in December, the doctor recommended that I take the meds twice a week, because my feet and legs had improved so much. Swelling of legs and feet where gone, then I had a follow up appt. In December,2021 and my after doctor summary the doctor write edema was gone. The January of 2022, my legs and feet started swelling, and they are bigger now than they every has been. I am no longer taking the Vasculera, and hoping that my legs will return back to how they were. I am also now getting other test done to see if there is any other health issue going on in my body..I.e. heart failure, kidney, or liver disease. I hope it was not the Vasculera."
"Some background that may be relevant to others: I was diagnosed with Melanoma about a decade ago and through surgeries, I had several lymph nodes removed in my right groin area. Consequently, I developed significant lymphedema in my lower right leg. I tried compression stockings, leg wraps at night, massage therapy, etc. All did very little to improve the swelling and reduce my misery. Then 3 years ago I found a vascular surgeon who put me on Vasculera. Because my symptoms were so bad, I took 2 pills a day for well over a year. But gradually I started noticing much less swelling in my leg. It took over a year, but it was really amazing to see the change. For the past 2 years I have reduced my dosage to one pill per day and my lymphedema remains well controlled. To me, this drug is life changing for the better. Oh and the cancer worries? I took this drug while receiving Keytruda for my melanoma and I am happy to say I am 2 years cancer free!"
"My vascular surgeon suggested that I take Vasculera for 3 months due to mild to moderate Phlebitis. It has helped calm down the painful symptoms of Phlebitis, however, I do experience some of the side effects that are listed and they do interfere with the quality of my life. I recently had blood labs drawn and my MCV levels are elevated. I checked the side effects symptoms again and it listed blood disorders as a possible side effect. I have never had any CBC elevated labs so I am very concerned and will be talking with my PC doctor as well as my vascular surgeon. I am also stopping the Vasculera until I get further instructions from my physicians. I would recommend Vasculera but strongly suggest to be aware of the side effects and act accordingly if the side effects are affecting the quality of your life."
For Dietary Supplementation "I started Vasculera almost 1 year ago, my legs don't ache like they used to. I don't want to be without it."
For Dietary Supplementation "Excellent results after just a few days! My legs look and feel so much better."
For Dietary Supplementation "Recommended by my vascular PA for leg cramps and it has worked for that. However, the swelling of my hands and feet is terrible. I am stopping for a while to see what happens,"
For Dietary Supplementation "I have insurance but the price is still high"
"I've been taking Vasculera for 1-2 years and it has reduced the size of my Hemorrhoids. I recommend Vasculera."
