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Generic Name: brimonidine-timolol

Brand Name: Combigan ophthalmic (eye)

Drug Reviews Drug and Medication User Reviews

Like a lot of other people have mentioned, it gives me dry mouth and makes me tired (which makes sense because one of the active ingredients is a beta blocker). You wouldn't think eye drops could give you full body side effects, but they certainly can. You can avoid it by either closing your eyes or blocking your tear ducts with your finger for a couple of minutes after application. This helps a ton in avoiding the systemic side effects. However, it easy to skip this and cut corners especially since you are doing it 2x day for the rest of your life if you have primary open angle glaucoma like I do.


While these eyedrops kept my pressure down to 17 and 19, the adverse side effects were very scary and troublesome. My eyes were embarrassingly red all the times. My eyes itched and burned. My left eye always felt like there was something in it. The skin around my left eye was dry, scaling and red. I met my eye doctor yesterday and she changed my eyedrops. I do not feel these Combigan eye drops should be prescribed to anyone. The FDA should take these off the market. They are not helpful but hurtful and dangerous.


Overall, it lowered my eye pressure to an acceptable level as my doctor described. The biggest complaint is the cost. Change from this combination drop to the two drops it consist of and my eye pressure is actually lower and the cost is significantly less.


However; I've experienced much weight gain, swollen legs And arms. It degrees keeps my pressure low. I also take Lantrspote with it. Lamppost once nightly, Combine 2x day.


I began with an IOP of 30 in each eye. I was prescribed Latanoprost once daily in each eye. After a month, Latanoprost had no effect. I was switched to Combigan. After 3 weeks using Combigan 2X daily, my IOP was down to 19 in each eye. I introduced 1 drop in each eye in the morning, and again in the evening about 12 hours later.


Combigan has lowered the intra ocular pressure in both eyes. However, I feel very tired and my blood pressure drops for 3-4 hours after each use.


My Doctor started me on Combigan in April 2017. About a month after starting, I experienced severe dizziness I could not even stand. For months I walk around feeling light headed. After about nine months of taking Combigan, I noticed my eye getting very red and my eyelid beginning to droop. It totally changed my facial appearance. I had to stop taking this medication. Even though it effectively decreased my eye pressure, the side affects were to too much..I no longer take this medication.


Development of macular edema after 3 weeks of use!! Dr discontinued immediately but still have residual issues!


Been taking Combigan for about 6 weeks; working great at reducing eye pressure, but noticed increased muscle pain and stiffness. Hurts to get out of bed and in and out of car and even to get up after sitting for an hour or more. I didn't relate it to Combigan and thought I may be getting arthritis but it was from neck to hamstrings. Has anyone else experienced the same symptoms? I am an overall healthy person.


Had IOL replacement after cataract surgery, optometrist felt my eye pressure was too high even while using Travatan Z and still on Prednisolone acetate ophthalmic drops. After threes using Combigan I began having a headache where even my scalp hurt, severe runny nose, watering eye, itching and inflamed severe redness around the eye lids,continuous coughing and from catch in my throat each time I would take a deep breath. After being on this 1 week I called the doctor and was advised to stop using Combigan.


Used drops for 5 days and developed heaviness in chest, as well as numbness in right hand and right leg felt asleep (like when you sit on your leg and it falls asleep). These sensations only lasted 5-10 seconds but are scary. Eye Dr. advised to discontinue drops and he thought I could have a heart attack it was not the drops. The symptoms occurred again after I stopped the drops (2 days) so I went to emergency room and ended up being admitted for nuclear stress testing. All testing was negative which is great, but I still have the numbness. Having cataract surgery in a couple of weeks and Dr. will insert stint so I don't have to use drops. Appears my symptoms are not attributed to the eye drops but wanted others to know my experience. I will discuss where to go from here with family Dr. Wishing the best in life to all.


my eyes are very very red is this normal and shold I be doing something to help the redness.


combined with azopt eye pressure went to normal range


It works, but it makes me very tired. The tiredness has become an issue, and I will seek other alternatives.


After a brief try, this drug made my fingers, ankles and knee became swollen to the point of pain and thinking I had broken my knee. I went off the drug and all swelling went away. Tomorrow I start something else. Sure hope it works.


As soon as I began using Combigan, I experienced a marked drop in blood pressure and pulse; my pulse which is normally 70 would fall to 45-50 within two hours of my having applied the Combigan eye drops. I would have to drink a cup of strong coffee in order not to suffer syncope. After using Combigan for 8 months, I developed a severe case of allergic conjunctivitis and my ophthalmologist insisted that I stop using it.


My dr recommended conbigan instead if timoptic xe. After 4 days my eyes cheeks very very swollen, blood red eyes, felt like someone had taken a blowtorch and needle to my eyes. Drained constantly causing a severe rash,blurred vision, no sleep due to pain. Quit taking drops


eye pressuer down


Even though this medication decreased the pressure in the eye, I went off of it b/c it felt like there was a piece of glass in my eye and it hurt everytime I blinked my eye! Discontinued using it over a week age and my eye is still scratchy and irritated. Opting for SLT


I have had ocular hypertension for 20 years. I have been on Xalatan for most of that time. It ceased to be effective, so my doctor had me switch to Combigan. It lowered my pressure, but I my eyes were very red and itchy. I also experienced blurry vision and lightheadedness, especially in the morning. I am switching to a different drug.