Brisdelle: Uses, Side Effects, Warnings, and Dosing Information

Generic Name: Brisdelle (paroxetine)

Brisdelle Reviews

For Hot Flashes "I've only been on it for a week, but before taking the medicine, I was up at least 3 times per night changing clothes due to being drenched from night sweats (very disruptive to sleep patterns). Since starting this medicine, I have not had one episode of night sweats! Hope it lasts, it will be a life changer if it does!"


For Hot Flashes "I have been taking Brisdelle for two weeks now, but had to stop taking it due to the unacceptable side effects. It worked like a charm on my hot flashes, reducing them from at least 12-15 times in a 24-hour period (with night sweats) to only 1 per day. However, I found it impossible to sleep, I could not keep my hands and feet still, I had congestion so bad that I thought I had a sinus infection, and also suffered blurred vision. I tried taking it in the morning instead of at night, but it made no difference to my insomnia. I have, therefore, discontinued it altogether."


For Hot Flashes "I took the medication for two weeks and it worked like a charm. However, I started to experience extreme pain in my joints (knees, ankles, wrist). Not sure if it is associated with the medicine, but I didn't have all of the aches until I started. I love how the medicine mellowed me out, no anxiety or frustration over little things. Hot flashes are at a minimum. Hope it makes it because I would like to continue taking it."


For Hot Flashes "I took it for 3 months straight. During the 1st month, my hot flashes reduced. By month 3, it seemed like it wasn't helping with the hot flashes much, but I noticed a positive side effect. My overall outlook on life was so much better. Little things that once got on my nerves slid off my back like a duck's. I asked for something different (grass is greener syndrome) because I wanted more. More hot flash reduction, less anxiety. When I stopped, I realized I'd made a terrible mistake. It's been 2 weeks, and I'm ready to kill somebody. Moody? Yes. Irritable? Yes. Sweating profusely? Yes. I'm getting back on it today!"


For Hot Flashes "I stopped having periods 10 years ago. Then I suffered from severe hot flashes in the first five years after. In the last five years, hot flashes really diminished but were triggered by anxiety, certain foods, and occasional night sweats. However, I could count on having at least one episode of night sweats per evening (down from as many as 7 to 10 a day - and leaving me drenched with my clothes soaked!). My GYN recommended Brisdelle two months ago. I am hypersensitive to all meds, so I was skeptical, in addition to being an RN. I don't like to take drugs of any kind, however, I was desperate. The Brisdelle worked immediately, and I haven't had one episode of hot flashes since. I just have dry mouth now. Very bad dry mouth!"


For Hot Flashes "I've been on Brisdelle for about 5 weeks, and I absolutely LOVE it!! I noticed the difference after about 4 days. I was a complete mess before starting Brisdelle (moody, depressed, major hot flashes, crying, etc.). I now feel like a brand new woman. I am so appreciative that my doctor prescribed this for me."


For Hot Flashes "I have been on this for 2 months. It has worked very well for my hot flashes and night sweats. I have noticed dry mouth and some headaches and some joint pain in my fingers, but that pain goes away during the day. It's worth it though, so I can sleep at night without being hot and cold all night and day long. I just drink more water."


For Hot Flashes "I started with horrific hot flashes, sweating all night, no sleep. Sweating in meetings, going out. Couldn't wear any makeup. I started taking Brisdelle about 6 months ago. I did my research. This medication is a lifesaver. It's expensive as hell, I found a coupon for it, and I only pay a quarter of what it costs. There was someone saying how terrific the withdrawal symptoms are, you need to be weaned off. Not every medicine you can just stop cold turkey. Read all inserts of medicines you are prescribed. Some meds take a while to get over side effects. This has been a lifesaver."


For Hot Flashes "I was suffering from severe hot flashes every 35-40 minutes all day, severe day and night sweats, chills, feeling hot and cold at the same time. I was extremely miserable. I could not go to work, my social and love life came to an abrupt end. I would get soaking wet and had to remove all clothing every 35-40 minutes. It was horrible! This went on for 3 months. Everyone kept telling me it was not going to last long, maybe just a few years. In no way was I going to go for years feeling that way. My doctor prescribed Brisdelle 7.5 mg 7 weeks ago, and my life is 90% back to normal. Once I started taking this medication, the sweats, chills, and severity of the flashes stopped. I only have mild flashes and hopefully, they will end too."


For Hot Flashes "I've been taking it for three weeks. It has reduced the number of hot flashes from 8-10 a day down to 2-4. Not great results, but better. I was hoping for an occasional hot flash, but daily. I will continue taking the medicine for three more weeks to see if the results improve."


For Hot Flashes "I am beyond furious. Not only did Brisdelle live up to its promise of eliminating night sweats and hot flashes, they failed to mention (as did my doctor) the side effects when stopping it. After 5 months of taking it, I decided it wasn't working for me. Now, I am left with what I have discovered are 'brain zaps.' There are other ways to help with these symptoms."


For Hot Flashes "This drug sort of helps with hot flashes, it diminished them by about 75%. However, the person who designed the packaging for this drug needs to be fired. I think that most of the expense for this product comes from the overdone packaging alone. The capsules are difficult to get out of the blister packaging. The cardboard wrapping is excessive and impossible to open without the help of scissors and a box cutter! Terrible, terrible, terrible..."


For Hot Flashes "Been on Brisdelle for ten days. I was having eight to ten hot flashes a day, and I was up all night long with them as well. Over the last ten days, they have tapered off, with yesterday and today being completely hot flash-free! My anxiety is also almost completely gone. I had bouts of nausea in the beginning that came in waves and even woke me up at night, but that seems to have disappeared completely. I hope this continues! I'm very happy with this medication."


For Hot Flashes "I've been on this medication for a year now, about a month after having a full hysterectomy. Worked the first night I took it. No hot flashes, no mood swings. I feel great and sleep well. I do experience nausea once in a while in the morning, but that fades fast with a drink of water or a cup of coffee. It's very pricey, even with a coupon, as I pay out of pocket, but it's worth every dime."


For Hot Flashes "I've been on Brisdelle for 8 days, and I feel like a new woman. No hot flashes in 5 days, my mood is much better, no night sweats, and no crying. I hope it lasts. I'm so glad my doctor prescribed this."


For Hot Flashes "My doctor prescribed this to help me with hot flashes and night sweats. After taking this for just three days, I was in bed with one of the worst headaches I've ever had. Seven hours, six ibuprofen, three aspirin, and three ice packs later, I still had it. On day four, I woke up feeling somewhat human, only to have it return with a vengeance within a few hours. By the end of the day, at a friend's home, I was on her bathroom floor and convinced I was dying. Not only was the headache almost unbearable, but I also had a stabbing pain in my left eye. My husband managed to get me home, but not before I threw up in the car. I had chills and pain all night long. After investigating the side effects, we've decided this is not the medication for me. The hot flashes and night sweats are bad, but they're not nearly as horrible as the pain I've been in."


For Hot Flashes "A GYN prescribed Brisdelle - it's a low-dose Paxil (7.5 mg) for hot flashes. This Doctor stated that unlike other SSRI's, I would NOT have complications or side effects going on/off them - in the case of running out of supply. This was NOT my experience. After 3-4 days of stopping, I noted an odd sensation connected to my eyes. I told my opthamologist about a "swishing" sound I heard with any movement of my eyes. I finally found others reporting this all over the internet. This also happened in a previous year with Sertraline (Zoloft) - this 'after quitting' side effect lasted a very long time - maybe a year or more! THE DUMBEST, MOST WASTEFUL PACKAGING ON THE PLANET. WHY NOT SIMPLY MAKE 7.5 PAXIL IN A SIMPLE BOTTLE? Pink? Come on!"


For Hot Flashes "The first couple weeks I slept like a baby. I still sleep like a baby only snore like a trucker. I really like how mellow I feel , less moody, over all happier. I started this medication to help with hot flashes. Now I don’t think I have but one a week, it was 2-3 a day. I think it’s really helped with the hot flashes. I’ve experienced some of the side affects, muscle - joint pain , breathing heavier than normal especially when I go to sleep. When I do fall asleep I sleep like I haven’t slept in decades oh that’s because I also have insomnia if I don’t take the medication. Sometimes I take it just to fall asleep. This can’t be good but what’s worse is my eye twitches like muscle spasms sometimes all day other times off and on through out the day. I’m over the eye twitching. I feel like I’d be better changing my wardrobe and having the hot sweats. Insomnia sucks...So does my eye twitching. I wish I’d never started this medication."


For Hot Flashes "Brisdelle definitely helped and calmed down the night sweats therefore, I gave a five rating. If I had to rate the side effects it would be a zero due to the severity. I experienced all the symptoms mentioned in other comments which includes vertigo symptoms with the room spinning a couple of nights, fatigue, swooshing sound in head, sensitivity to light, headaches, etc. I have been off this medicine three weeks and still feeling fatigue, nauseous, light headedness, head tremors/zaps and most of all feeling weird. I believe I rather deal with the hot flashes instead of going through all this drama. I gave it a try and it's not for me."


For Hot Flashes "My hot flashes were terrible. A lot during the day and at least 6 - 8 at night. Waking me up, so can't get enough sleep. I took the brisdelle and at first I didn't think it was working. About 4 weeks in, I noticed a big change and now I'm 7 weeks in and have not had one hot flash in the last three weeks. I'm sleeping again and not sweating all day long. The only drawback was the first 3 weeks. I was exhausted, had some muscle twitching and a backache. All gone now, but getting used to it was not easy but worth it."


For Hot Flashes "Holy Hell is exactly how I feel. I had been taking Brisdelle for 1.5 years. The hot flashes did indeed subside - however, the side affects of this medicine coupled with the fact Noven was acquired by YET another pharmaceutical company - YOU CAN'T PLACE A REP IN THE AREA, DISTRIBUTE YOUR DRUGS, AND THEN FIRE HER-AND NOT REPLACE THEREFORE there is NO medicine or support here. You dumped this drug in the Dr's hands and walked away. After calling Sebula - you act like you don't even care. You have made it impossible to obtain this. I happen to think this is illegal. I just decided to wean myself off this and Premarin. It has been nothing short of a nightmare. If you don't need this drug- DON'T START. Seriously."


For Hot Flashes "Only took one dose. Achy the next morning. 22 hrs after dose dizziness and weakness. My husband could barely get a BP on me and when my pulse came up enough to register it was only 54. I vomited then sweat profusely. My knees hurt severely for an hour. Hot flashes were diminished for the next 3 days. Fine now but still having hot flashes."


For Hot Flashes "Was given RX for hot flashes, had shock at price (90 day over $200. asked Dr. to write RX for Paxil 10 mg, use pill cutter to cut 1/2 then 1/2 of a half = 7.5 ,90 day $4.ish.) Works for me. Hot flashes not as harsh or as often. Worried tho when I do try to wean myself, I have experienced weird sensations when have forgotten to take for a few days."


For Hot Flashes "I have been taking Brisdelle for 1 year. Hot flashes are mostly gone, I have one occasionally usually in the morning. I ran out and my DR had written prescription for 1 year. I had to call and wait 4 days for the refill. Holy cow was I miserable and within 2 days the flashes were back full force. I am back on it. I do have joint pain in my ankles in the morning, not sure if its the drug or not but interesting others have the joint pain. I also am struggling to lose weight when it used to be so easy, Brisdelle to blame or menopause or both. Its a good drug and does what it says for me. I will continue taking it. By the way I have a coupon from their website and only pay $25 a month for it. It is costly w/no coupon."


For Hot Flashes "Brisdelle - SUCKS - Why prescribe a medication to help you with the hot flashes YET make you feel miserable (side effect) HEADACHES, nausea, trembling eye, Ewwwww. Really... I rather go thru the hot flashes. BAD BAD medicine. Also I was puking up."

More about Brisdelle (paroxetine)

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  • FDA approval history
  • Drug class: selective serotonin reuptake inhibitors
  • Breastfeeding

Patient resources

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Other brands

Paxil, Paxil CR, Pexeva

Professional resources

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  • PARoxetine (AHFS Monograph)

Other brands

Paxil, Paxil CR, Pexeva

Related treatment guides

  • Hot Flashes
  • Postmenopausal Symptoms

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