Pravachol: Uses, Side Effects, Warnings, and Dosing Information

Generic Name: Pravachol (pravastatin)

Pravachol Reviews

For High Cholesterol "Within 2 weeks of being on 40 mg of Pravachol, I began noticing muscle weakness in my shoulders, wrists, and knees. I later discovered that these are possible side effects of this medication. I noticed remarkable improvements after stopping the medication."


For High Cholesterol "Lowered my bad LDL from 180 to 95 in 6 months, on only 20 mg daily. Only side effect is my legs get sore when I walk distances that never bothered me before. However, with a little rest, I'm okay. Pravachol is MUCH better than Lipitor, which I threw away after a week due to leg and joint pain."


For High Cholesterol "I've taken atorvastatin, Crestor, Zetia, and then Pravachol for nearly five years after quadruple bypass surgery (no previous symptoms, discovered need on X-ray for pneumonia!). Except for Zetia, which is not a statin and did NOTHING for my cholesterol, which was not excessively high anyway, ALL three others have given me SEVERE muscle pain, mostly in my calves and biceps, making me move as if I were quite elderly and collapsing under me without notice. The pain is unrelenting, even in bed at night. 20% supposedly have this reaction, and most stop taking the statin—my cardiologist threatens me, saying I can't, so I've given myself my second shot of Repatha (not a statin) in the belly (cost/once a month/$1000 without insurance, $355 with mine). Lousy price to pay (not a play on words) for lowering cholesterol—excruciating pain or lots of dollars...IF the shot works!"


For High Cholesterol "Took Pravachol for 6 months and immediately had an achy pain in my legs. I walk a lot all day because I walk my dog. After taking this medication, I had to ask my husband to walk her often because the pain was too great for me to walk her. I'm 72 years old, female, and I have always been very active. I could not continue Pravachol because of the pain level. I stopped with my doctor's approval for 6 months. My cholesterol shot back up to a very high rate, as before. I have restarted this medication and will see the doctor in three months. I hope there is another medication for cholesterol that I may take without negative side effects. It does work well and did reduce my cholesterol. I took 10 mg tablets."


For High Cholesterol "Medicine was fine at 20mg dose. When my doctor increased the dose to 40mg, I started having increased muscle stiffness, especially in the morning."


For High Cholesterol "It lowered my cholesterol without any side effects."


For High Cholesterol "It has done the job in lowering my cholesterol within 3 months."


For High Cholesterol "joint stiffness, muscle weakness"


For High Cholesterol "Does anyone experience coughing and wheezing issues with pravachol?"


For High Cholesterol "It appears to work for my situation."


For High Cholesterol "Does the job. Lowered my cholesterol to normal levels."

More about Pravachol (pravastatin)

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  • Latest FDA alerts (4)
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  • Dosage information
  • During pregnancy
  • Drug class: statins
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Patient resources

  • Pravachol drug information

Professional resources

  • Pravachol prescribing information
  • Pravastatin (AHFS Monograph)

Related treatment guides

  • High Cholesterol
  • High Cholesterol, Familial Heterozygous
  • Hyperlipoproteinemia
  • Hyperlipoproteinemia Type III, Elevated beta-VLDL IDL

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