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Generic Name: Primlev (acetaminophen-oxycodone)

Primlev Reviews

For Chronic Pain "According to my pain doctor, companies have a 20% allowable variance in the active ingredient. That is horrible! So they put me on a brand of oxycodone/acetaminophen called Primlev 10/300, and it has been amazing! It actually works. I have tried all the other manufacturers, and this one blows them all away."


For Chronic Pain "After being on hydrocodone for a few years, I was switched to Primlev. I have had no side effects at all and it helps with my chronic pain much more than hydrocodone, and I like the fact that it has only 300mg of acetaminophen. I do find that I need to take it more like every 4-5 hours instead of every 6 hours, but I've read that the effects do begin to wear off after 3.5-5 hours. Overall I consider this medication a godsend"


For Pain "Primalev 10mg/300mg has been a lifesaver for me. I was born with a rare orthopedic birth defect that causes severe deformities in most of my bones, joints and muscles. This disability alone causes tremendous pain. However, just 3 years ago I was diagnosed with having Fibromyalgia that also contributes to my pain. Both conditions required me to stay in bed, usually tossing and turning until morning where I needed large amounts of caffeine to manage the day. One day my PCP prescribed a new medication, Primalev. Primalev has given me my life back. It has nearly stopped all of my pain and I am forever grateful. My only complaint is only 1 pharmacy offers this miracle medication. Please don't discontinue making this medication."

More about Primlev (acetaminophen / oxycodone)

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  • Drug class: narcotic analgesic combinations

Patient resources

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Professional resources

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