Generic Name: Votrient (pazopanib)
Votrient Reviews
For Renal Cell Carcinoma "Have been on Votrient now for over three years and am in remission. Side effects have included hand and foot pain (very slight now) and have experienced weight loss (from 180 lbs to around 130 lbs) over the last three years. As of this year, there have been no signs of liver problems but have had minor digestion issues. It appears that Votrient has been successful - unlike my experience with Sutent, Avastin, Xeloda and Affinitor. I had been diagnosed with stage IV renal cell carcinoma-sarcomatoid in 2008, and had the left kidney removed (and spleen due to a fall in the hospital). I have been on Votrient now for the better of three years, am still employed and fully functional."
For Renal Cell Carcinoma "I have taken Votrient since 9/2010, starting at 800 mg per day, but reducing dosage to 400 mg then 200 mg due to high liver enzyme counts. I started taking Votrient after my kidney was removed due to RCC, in addition, I had three tumors in my legs, which is how I found out I had RCC. After taking Votrient and the kidney removal, two of the tumors disappeared. One year later and after taking the drug for one year, I had the third tumor removed by surgery, which was reduced in size by 50%. Today, my latest scans are showing no new cancer sites. Side effects have been minimal - diarrhea and change in taste with higher dosages, plus a stylish looking white hair! This medicine has allowed me to continue traveling and enjoy life without any limits."
For Renal Cell Carcinoma "I have been on Votrient since Jan 2010. Started with a right kidney in 1999. In 2009 my family doctor suggested that I have a pulmonary doctor run some CTs to see what he thought. After 8 months of CTs, I had to go and get a biopsy and it proved 2 clear and 2 renal cell carcinoma had appeared between my lungs. I checked a couple of oncologists in town. Been on the medicine since January 2010 and have little significant change. A little diarrhea once in a while and headaches, some dizziness on occasion but no significant change. Feel real good about the treatment. Would recommend it to anyone."
For Soft Tissue Sarcoma "I was diagnosed with 4 fibrosarcoma tumors in my liver on July 15, 2014. I did 6 weeks of GEMS/Taxol, and after the scan showed two more tumors in the liver and four now in my lungs. My doctor put me on Votrient and scanned me once again after six weeks. All the tumors in my lungs have shrunk to half their size, and one tumor in the liver has also shrunk to half its size, while all the others in the liver are dying from the inside out."
For Renal Cell Carcinoma "I have been taking 800mg of Votrient daily since March 2012 to treat Renal Cell Carcinoma tumors, which developed when the cancer spread from a large tumor on my right kidney. Votrient has been effective in stopping the growth of the tumors and shrinking a few. Side effects experienced: treatable elevated blood pressure and diarrhea."
For Renal Cell Carcinoma "On Votrient since 2010 after Sutent. Results were good. After six months - no sign of metastasis and have been in remission since 2012. Votrient had the effect of high blood pressure which was mitigated by Procardia. As of late, have lost weight and am having some digestive issues."
For Renal Cell Carcinoma "I started on Votrient on May 4, 2013. I take it at bedtime, which has really helped. I took it for about 24 days back in December, during the day, and side effects were far worse. So far, the side effects are more tolerable than Sutent. I do have high blood pressure and low platelets, but the doctor is doing labs weekly. Some days the side effects are worse than others. I went up to 800 mg last week and have more fatigue. I pray it works for my lung tumors as I have heard it has for others."
For Renal Cell Carcinoma "I was diagnosed with renal cell carcinoma in May 2015. I had my right kidney removed due to a huge tumor. The cancer metastasized to my lungs. I tried several treatments that did not work. Finally, I was prescribed Votrient! It worked immediately. I have been using it for about 7 months. The only side effect I experienced was high blood pressure. I just had a scan a week ago, and the tumors are still shrinking or have gone away. I will continue to pray to God for your positive progress as well as mine. Stay positive and know that you will beat it!"
For Soft Tissue Sarcoma "Felt it is time for an update. It's April 26, 2014, and I've been on Votrient since August 2012. So far, tumors remain stable and continue to show shrinkage. I'm still taking the same dosage, 800mg per day."
For Renal Cell Carcinoma "I have been taking Votrient since Fall 2015. Bilateral Renal cell carcinoma. Left total nephrectomy and partial right. Small spot on liver at that time. Remaining tumors on the right. Due to surgery complications after right kidney surgery, sepsis, heart attack, and stroke. I am now 59 years old. Votrient 800 mg daily for about 5 weeks was rough...but I would do it again. Vomiting, diarrhea, high blood pressure, body tired all the time. My hair has turned white, most people like my highlights! My oncologist has been wonderful and I have responded well to lower doses of Votrient which has helped my side effects. September 2016 I received great news! I am cancer-free. Continue on maintenance dose right now of 200 mg 3x/wk."
For Renal Cell Carcinoma "Began 800mg in May 2014, 10 months into treatment. No new mets at this time. High blood pressure began three weeks into treatment, a good sign in that it demonstrates the drug is working well. Hand-foot syndrome, initially intense pain, but now under control. Weight loss due to loss of taste and appetite, a nutritionist can help. White hair. This is considered the least toxic targeted therapy drug for mRCC, do all you can to stay with it. If it is working for the first year, you may continue to get excellent results for years to come. This is currently considered the first-line therapy for mRCC. Take at night to reduce the stomach discomfort."
For Soft Tissue Sarcoma "I was diagnosed with stage 4 Leiomyosarcoma on July 16, 2013. Tumors in my stomach, liver, and a few affected lymph nodes. Had surgery and removed 40% of my stomach on August 30, 2013. Surgery was a success. I Underwent 4 1/2 months of chemo with minimal shrinkage to existing tumors but did stunt the growth of the tumors. At that point, my tumors were considered inoperable. Started Votrient on February 14, just found out my tumors have shrunk enough on my liver to be operable. Liver Surgery scheduled on October 14. So happy, praying Votrient is our miracle. Good luck to others with my condition."
For Renal Cell Carcinoma "50-year-old male diagnosed with Stage IV mRCC on 1 May 2014. Radical nephrectomy of right kidney in June 2015. Tumour had invaded surrounding fat, IVC, and adhered to bowel. Metastases appeared in January 2015 (liver). Started 800mg Votrient in February 2015; side effects included white hair, gastric issues, loss of taste, high blood pressure, otherwise felt okay. After 1 month, high liver enzymes forced me to stop. After 4 weeks off, recommenced 400mg of Votrient. Side effects not as severe but similar to 800mg dose. Required a week off Votrient recently due to a bout of pneumonia. Liver metastases have shrunk from 20mm to 7.5mm since January, 400mg seems to be working, let's hope it stays that way."
For Renal Cell Carcinoma "Just started taking Votrient 09-15-11 for renal cell carcinoma stage 4, cyst in my spine and leg, no side effects as of yet. Looking forward to a positive experience and good reports on the medicine. Wish me luck."
For Renal Cell Carcinoma "Votrient was effective in shrinking tumors in lungs and inhibiting progression of tumors in spine and brain; but I had to discontinue it due to elevated liver enzymes. This happened with an 800 mg dose and a reduced dose of 400 mg. Side effects experienced early in treatment included elevated blood pressure (treated) and fatigue (tolerable)."
For Soft Tissue Sarcoma "I am currently battling mesenchymal chondrosarcoma. It originated in my right thigh in 2008, had the tumor removed, was cancer-free for 3 years, then was diagnosed last year with it again, with 5 tumors this time which had spread in my pelvic area, right lung, and right armpit (July 2012). I've tried a few chemotherapy treatments and during that time frame, the tumors grew plus one new one appeared. In August 2012, I was placed on Votrient (800 mg), the tumors stopped growing and have been stable ever since. My last scan was June 11, 2013, and all 6 tumors are still holding stable and have shown some shrinkage. The side effects come and go, I am experiencing more muscle pain throughout my body and still some nausea, but that's easily controlled."
For Renal Cell Carcinoma "My husband started Votrient 800mg about a week ago after surgery for metastatic renal cancer. So far, he is doing well, taking it at night seems to be working. Some mornings he is a little spent, but he does stay up late. I am praying for a good result - he has numerous tiny lung lesions and just a small area where the left kidney had been. He is 53 and otherwise in very good health."
For Renal Cell Carcinoma "RCC detected May 2018. Left kidney removed 20 years ago, started Votrient 800 mg on June 1, 2018. First follow-up PET scan will be August 30th, to see how it is doing. Most side effects, diarrhea most days, hair turning white, bruising easily, now feet are very tender, even though I am following instructions on applying urea lotion on both feet and hands twice daily. Take the Votrient first thing out of bed in the AM, with hopes I flush out early enough to have an active life, although I am limited some days, but must always know where restrooms are. When I started the Votrient, I went directly to 800 mg, and have stayed on it daily since. I feel that I must tough it out, and stay with it, to give it the best chance to work. Praying for good scan results. God bless you folks that are in the same fight, stay on meds, stay as active as you can (I walk 20-30 minutes every day), and eat to keep weight up which will help with your strength. My prayers are with you."
For Renal Cell Carcinoma "Unfortunately, side effects for me have been horrific! I was on 800mg for 6 weeks. I wound up with nausea, extreme hoarseness, high blood pressure, fatigue with sleeping 18 to 22 hours a day. Took a turn for the worse and liver enzymes were high. Could not eat or drink water for 5 days and lost 30 pounds. I was off the Votrient for a month and just started back on half the dose, 400mg. So far so good, one evening of slight nausea. Other than a little more tired, it appears to be better."
For Renal Cell Carcinoma "I had my right kidney removed in December 2014. They thought all the cancer was gone, but a few months later they found cancer in my lymph nodes. I started on Votrient in July 2015 at 800 mg but had my doctor reduce the amount because of stomach issues. I'm still nauseated daily and throw up almost every day. My hands are bright red, my hair is white, and I have sores on certain parts of my body that act like blisters then go away after a few weeks. All in all, the cancer is shrinking, and I have another CAT scan this month."
For Soft Tissue Sarcoma "I have started taking Votrient about three weeks ago. One tablet in the morning, one tablet in the afternoon, and one tablet before bedtime. I would be sick during the day (nausea, extreme fatigue, and no appetite.) I told my doctor about my experience and she suggested to take the tablets all at once before going to bed. I have been doing this for a week, and it is not too bad except waking up in the morning feel exhausted. But in the afternoon I would feel fine. I think the medication is working because I always have tumor pain and I will be going to the doctor this week for signs of some shrinkage."
For Soft Tissue Sarcoma "After four failed chemo regimens, the doctors decided to try Votrient. The first week or two was the toughest. The worst side effect was the tumor pain, which was in my chest and back. Additionally, there was some fatigue, loss of appetite, and diarrhea. Three months later (now), I feel well, and there has been some slight shrinkage of my tumors. I'm also back in the gym. White hair kicked in within the first month. I'm a 22-year-old covered in white hair, lol."
For Renal Cell Carcinoma "I was diagnosed with Stage IV renal cell carcinoma in January 2012. After two unsuccessful IL-2 treatments, I started taking Votrient in June 2012. At first, I had all of the written side effects, but after completely changing my diet, they diminished significantly. Fatigue and whitening of my skin being my only problems. My last CTs continue to show all of my known tumors as principally stable. The drug works for me! Five years and counting!"
For Renal Cell Carcinoma "I am taking Votrient for 14 days. My side effects are vomiting, some stomach problems, and a temperature around 37℃. Half of my left kidney was removed in June 2015, but a year after I got results that I have MS on my sternum bone and 2 tumors appeared in the soft tissues around the sternum. After 14 days, one of the tumors is getting smaller, I hope this will happen with the other one. Reading the other comments, I hope the side effects will go away and the tumors will be gone. I am 23 years old. God bless everyone."
For Renal Cell Carcinoma "Diagnosed on Jan 2, 2015, with renal cell carcinoma. I'm 61 and have been a picture of health my whole life. The right kidney had a tumor that they were going to remove until they found 2 lesions on my liver. The first medication I did not respond to, and I have been on Votrient for 2 weeks. After 1 week, they felt I was responding. The side effects are bad, with vomiting and diarrhea that drain me. It's hard to eat, as food doesn't taste right, and now my tongue has a burnt taste, so nothing tastes good, and I have lost a lot of weight in a short period of time. I sleep 10-12 hours a night and take a 2-hour nap. They say this is all typical for everyone. How long has it taken everyone to finally get back to feeling normal? I use a walker around the house and a wheelchair for the doctor."
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