Temodar: Uses, Side Effects, Warnings, and Dosing Information

Generic Name: Temodar (temozolomide)

Temodar Reviews

For Glioblastoma Multiforme "Have taken a reduced dose of Temodar (Temodol in UK) for 12 years on a five-week cycle. Side effects are bad - nausea, vomiting, fatigue, etc. However, I have MRI scans every 8 weeks and so far no recurrence."


For Anaplastic Astrocytoma "I was diagnosed with an anaplastic astrocytoma about 18 months ago. I had 6 weeks of radiation, then started on Temodar. I take 300 mg for 5 days every 4 weeks. I have one cycle to go. My last 2 MRIs have been clear. So far I would say this medication is working very well. As long as I take my anti-nausea medication about 30 minutes before the Temodar, I am fine. I take it at night right before I go to bed."


For Anaplastic Astrocytoma "I had taken temodar for anaplastic astrocytoma who grade 3. Took radiation ,7 weeks temodar during radiation days 100 mg per day, then 400 mg on every day for 5 days in 28 days cycle. After completing this dose for a year it came to know that the medication did not worked and new growth of tumor found. Then dosage changed to 100 mg daily but that also could not stop growth of the tumor but moderately grown as revealed In MRI scans done twice in 4 months"


"After 18 infusions (every 3 weeks) of Keytruda, my body couldn't handle the side affects anymore, so my Dr put me on Temodar for my metastatic melanoma - it's been over 3 years now, and my Dr said this drug is working for me - minimum side affects, I'm on a 28 day cycle, 5 days of the pill (200mm) and coast the next 23 days. When I take this drug, I also take compazine for nausea."


For Melanoma, Metastatic "After surgery (right axillary nodes), radiation of that site, subsequent CT scans and biopsy revealed that it had spread to his right lung. After treatment with this oral chemo (covered by Medicare), he has a complete remission of the lung tumor. Side effects were minimal. He is BRAF positive, although I don't know if that has any connection with the Temodar."


For Anaplastic Oligodendroglioma "Oligoastrocytoma WHO II: It stopped the growth of the brain tumor that I've been fighting for ten years. I'm one of the lucky ones. Keep fighting."


For Anaplastic Oligodendroglioma "It saved my life--what can I say?"

More about Temodar (temozolomide)

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  • FDA approval history
  • Drug class: alkylating agents
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Patient resources

  • Temodar drug information
  • Temodar (Temozolomide Intravenous) (Advanced Reading)
  • Temodar (Temozolomide Oral) (Advanced Reading)
  • Temodar (Temozolomide Capsules)

Professional resources

  • Temodar prescribing information
  • Temozolomide (AHFS Monograph)

Related treatment guides

  • Glioblastoma Multiforme
  • Anaplastic Astrocytoma

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